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TPM2 protein, human

Known as: beta tropomyosin, human, Tropomyosin Beta Chain, tropomyosin 2 (beta) protein, human 
Tropomyosin beta chain (284 aa, ~33 kDa) is encoded by the human TPM2 gene. This protein plays a role in muscle contraction.
National Institutes of Health

Related topics

Related topics

13 relations
Actin myofilamentActin-Binding ProteinCell MovementCytokinesis

Broader (1)

Tropomyosin

Papers overview

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Highly Cited
2005
Highly Cited
2005
Self‐organization of rat cardiac cells into contractile 3‐D cardiac tissue
The mammalian heart is not known to regenerate following injury. Therefore, there is great interest in developing viable tissue… 
Highly Cited
1997
Highly Cited
1997
The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer‐dependent splicing of the β‐tropomyosin alternative exon 6A
Exons 6A and 6B of the chicken β‐tropomyosin gene are mutually exclusive and selected in a tissue‐specific manner. Exon 6A is… 
Highly Cited
1993
Highly Cited
1993
In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism
Highly Cited
1993
Highly Cited
1993
Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF
The essential splicing factor SF2/ASF and the heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) modulate alternative splicing… 
Highly Cited
1992
Highly Cited
1992
Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.
Highly Cited
1991
Highly Cited
1991
RNA secondary structure repression of a muscle-specific exon in HeLa cell nuclear extracts.
The chicken beta-tropomyosin pre-messenger RNA (pre-mRNA) is spliced in a tissue-specific manner to yield messenger RNA's (mRNA's… 
Highly Cited
1986
Highly Cited
1986
Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation
The molecular basis for the expression of rat embryonic fibroblast tropomyosin 1 and skeletal muscle beta-tropomyosin was… 
Highly Cited
1983
Highly Cited
1983
Regenerating adult chicken skeletal muscle and satellite cell cultures express embryonic patterns of myosin and tropomyosin isoforms.
Highly Cited
1980
Highly Cited
1980
A comparison of the amino acid sequences of rabbit skeletal muscle alpha- and beta-tropomyosins.
Elucidation of the complete amino acid sequence of rabbit skeletal beta-tropomyosin has shown that it has the same number of… 
Highly Cited
1974
Highly Cited
1974
Chemical and immunochemical characteristics of tropomyosins from striated and smooth muscle.
1. On electrophoresis in dissociating conditions the tropomyosins isolated from skeletal muscles of mammalian, avian and… 
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