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TNK2 gene

Known as: TNK2, ACTIVATED p21CDC42 KINASE, ACK1 
This gene is involved in the negative regulation of cell growth.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Differentiation processCell ProliferationHomo sapiensPhosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Overexpression of activated Cdc42-associated kinase1 (Ack1) predicts tumor recurrence and poor survival in human hepatocellular carcinoma.
2011
2011
The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.
The non-RTK (receptor tyrosine kinase) ACK1 [activated Cdc42 (cell division cycle 42)-associated kinase 1] binds a number of RTKs… 
2011
2011
[Correlation study of the overexpression of activated Cdc42-associated kinase 1 and the stage and prognosis of esophageal squamous cell carcinoma].
OBJECTIVE To investigate the expression and relationship of activated Cdc42-associated kinase 1 (ACK1) and the clinical… 
2010
2010
ACK pushout to achieve TCP fairness under the existence of bandwidth asymmetry
On a bandwidth asymmetric link, such as an ADSL cable or a wireless link over an IEEE802.11-based wireless LAN, TCP flows are… 
2010
2010
Evaluation of TCP Acknowledgment Mechanism Influence on Router Performance
The efficient usage of congestion control becomes significant as Internet traffic grows. The quality of congestion control… 
2007
2007
Double mutant cycle thermodynamic analysis of the hydrophobic Cdc42-ACK protein-protein interaction.
Protein-protein interactions such as those between small G proteins and their effector proteins control most cell signaling… 
2005
2005
Specificity determinants on Cdc42 for binding its effector protein ACK.
Cdc42 and Rac are highly homologous members of the Rho family of small G proteins that interact with several downstream effector… 
2005
2005
Performance Improvement of TCP using Performance Enhancing Proxies — Effect of Premature ACK Transmission Timing on Throughput —
In order to improve TCP performance, a method using a PEP (performance enhancing proxy) is proposed. The PEP operates on a router… 
2004
2004
Identification of the Region in Cdc42 That Confers the Binding Specificity to Activated Cdc42-associated Kinase*
The Rho family small G-protein Cdc42 has been implicated in a diversity of biological functions. Multiple downstream effectors… 
Highly Cited
1996
Highly Cited
1996
Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells.
Degenerate PCR was employed to identify novel tyrosine kinase genes from an enriched population of human umbilical cord blood… 
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