Skip to search formSkip to main contentSkip to account menu

TNFSF10 wt Allele

Known as: Tumor Necrosis Factor (Ligand) Family, Member 10 Gene, Apo-2L, Tumor Necrosis Factor Ligand Superfamily, Member 10 Gene 
Human TNFSF10 wild-type allele is located within 3q26 and is approximately 18 kb in length. This allele, which encodes tumor necrosis factor ligand… 
National Institutes of Health

Related topics

Related topics

14 relations
3q26ApoptosisCaspase Cascade PathwayCell Death

Broader (1)

TNFSF10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.
Received 17 August 2004 Accepted 7 January 2005 Although hepatic injury is reported in cases with dengue haemorrhagic fever and… 
2010
2010
A Genetically Encoded Multifunctional TRAIL Trimer Facilitates Cell-Specific Targeting and Tumor Cell Killing
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL, Apo2L) has been shown to exhibit potent and specific apoptotic… 
2008
2008
Synergism of CPT-11 and Apo2L/TRAIL against Two Differentially Sensitive Human Colon Tumor Xenografts
Objective: The ability to sustain and grow portions of human tumors as xenografts in SCID mice provides a valuable preclinical… 
Review
2007
Review
2007
Apo2L/TRAIL and immune regulation.
Apo2L/TRAIL is a member of the TNF family, with its receptors DR4 and DR5 containing a death domain. Multiple tumors are… 
2006
2006
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria…
Apo2L/TRAIL is actively investigated as a novel targeted agent to directly induce apoptosis of susceptible cancer cells. Apo2L… 
2006
2006
The Essential Role of the Mitochondria‐Dependent Death‐Signaling Cascade in Chemotherapy‐Induced Potentiation of Apo2L/TRAIL Cytotoxicity in Cultured Thoracic Cancer Cells: Amplified Caspase 8 Is…
PURPOSEDespite adequately expressing functional receptors for tumor necrosis factor receptor apoptosis-inducing ligand (TRAIL… 
2006
2006
Apo2L/TRAIL pharmacokinetics in a phase 1a trial in advanced cancer and lymphoma.
3047 Background: Apo2L/TRAIL (Apo2L ligand/tumor necrosis factor-related apoptosis-inducing ligand) is the first recombinant… 
Highly Cited
2001
Highly Cited
2001
Molecular Cross-talk between the TRAIL and Interferon Signaling Pathways *
TRAIL/APO-2L induces apoptosis in a variety of transformed cells and has potential as an anti-cancer therapeutic. The physiologic… 
Review
2001
Review
2001
Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma and other neoplasias
TNF-related apoptosis inducing ligand/Apo2 ligand (TRAIL/Apo2L) is a member of the TNF superfamily of death ligands that… 
2000
2000
Induction of apoptosis in glioma cell lines by TRAIL/Apo‐2l
TRAIL/Apo‐2L, a novel cytokine, is a member of the tumor necrosis factor (TNF) family and serves as an extracellular signal… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)