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TNFRSF6B gene

Known as: DcR3, TR6, Tumor Necrosis Factor Receptor Superfamily, Member 6B, Decoy Gene 
This gene plays a regulatory role in receptor-mediated apoptosis.
National Institutes of Health

Related topics

Related topics

11 relations
ApoptosisCell SurvivalCytokine Signaling ProcessIntercellular Communication Process

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TNFRSF6B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Polymorphisms of decoy receptor 3 are associated with risk of esophageal squamous cell carcinoma in Chinese Han
Decoy receptor 3 (DcR3) is a soluble receptor without transmembrane and intracellular sequences in its peptide. It can bind to… 
2009
2009
The Decoy Receptor 3 (DcR3, TNFRSF6B) suppresses Th17 immune responses and is abundant in human cerebrospinal fluid
2009
2009
DcR3 protects THP-1 macrophages from apoptosis by increasing integrin alpha4.
2007
2007
Decoy receptor 3 ameliorates an autoimmune crescentic glomerulonephritis model in mice.
Autoimmune crescentic glomerulonephritis (ACGN) is a variant of crescentic glomerulonephritis. The outcome of treatment of… 
2007
2007
Attenuation of Bone Mass and Increase of Osteoclast Formation in Decoy Receptor 3 Transgenic Mice*
Decoy receptor 3 (DcR3), a soluble receptor for FasL, LIGHT, and TL1A, induces osteoclast formation from monocyte, macrophage… 
Highly Cited
2005
Highly Cited
2005
Attenuation of Th1 Response in Decoy Receptor 3 Transgenic Mice1
The soluble decoy receptor 3 (DcR3) is a member of the TNFR superfamily. Because DcR3 is up-regulated in tumor tissues and is… 
Highly Cited
2004
Highly Cited
2004
Enhanced adhesion of monocytes via reverse signaling triggered by decoy receptor 3.
2003
2003
Pharmacokinetics, metabolic stability, and subcutaneous bioavailability of a genetically engineered analog of DcR3, FLINT [DcR3(R218Q)], in cynomolgus monkeys and mice.
Decoy receptor 3 (DcR3) is a novel member of the tumor necrosis factor receptor superfamily, which binds to and blocks the… 
2001
2001
Soluble Fas and cancer.
Recent studies have revealed an anticipated link between a soluble receptor antagonist for the proapoptotic protein Fas and… 
Highly Cited
2000
Highly Cited
2000
Over‐expression of the decoy receptor 3 (DcR3) gene in peripheral blood mononuclear cells (PBMC) derived from silicosis patients
Dysregulation of apoptosis, particularly in the Fas/Fas ligand (FasL) pathway, is considered to be involved in the pathogenesis… 
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