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TNFRSF12A protein, human

Known as: TweakR, Tumor Necrosis Factor Receptor Superfamily Member 12A, fibroblast growth factor inducible-14 protein, human 
Tumor necrosis factor receptor superfamily member 12A (129 aa, ~14 kDa) is encoded by the human TNFRSF12A gene. This protein is involved in both… 
National Institutes of Health

Related topics

Related topics

17 relations
Angiogenesis PromoterApoptosisApoptosis Regulatory ProteinsCytokine Receptor Gene

Broader (1)

TNFRSF12A protein

Papers overview

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2014
2014
Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR
TweakR is a TNF receptor family member, whose natural ligand is the multifunctional cytokine TWEAK. The growth inhibitory… 
2013
2013
TNF-Like Weak Inducer of Apoptosis (TWEAK) Promotes Beta Cell Neogenesis from Pancreatic Ductal Epithelium in Adult Mice
Aim/Hypothesis The adult mammalian pancreas has limited ability to regenerate in order to restore adequate insulin production… 
Review
2012
Review
2012
The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting
The occurrence of skeletal muscle atrophy, a devastating complication of a large number of disease states and inactivity/disuse… 
2012
2012
Expression of p53-regulated proteins in human cultured lymphoblastoid TSCE5 and WTK1 cell lines during spaceflight.
The aim of this study was to determine the biological effects of space radiations, microgravity, and the interaction of them on… 
2012
2012
[Effect of dexamethasone on expressions of TWEAK and Fn14 in the lung of asthmatic mice].
AIM To investigate the effect of dexamethasone (Dex) on the expressions of TNF-like weak inducer of apoptosis (TWEAK) and… 
2011
2011
TWEAK and TNF regulation of sclerostin: a novel pathway for the regulation of bone remodelling.
TNF-ligand and TNF-receptor family members have established essential roles in the regulation of bone remodelling. We showed… 
2011
2011
Molecular Cloning, Phylogenetic Analysis, Tissue Distribution, and Expression of the Cytokine TWEAK in Zebrafish (Danio rerio)
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK; also known as Apo3L, TNFSF12, CD255) is a member of the TNF… 
2011
2011
Abstract C18: A phase I study of enavatuzumab (PDL192, ABT-361), a first-in-class human monoclonal antibody targeting TWEAK (tumor necrosis factor-like inducer of apoptosis) receptor, in patients…
Background: TWEAK receptor (TweakR, TNFRSF12A, CD266) is a member of the TNF receptor superfamily and is expressed on a range of… 
2010
2010
[The expression of TWEAKR/Fn14 in Rheumatoid arthritis fibroblast-like synoviocytes].
AIM To investigate the mechanism of TWEAK on Rheumatoid arthritis fibroblast-like synoviocytes (RA FLS) activation and articular… 
2006
2006
TWEAK shall inherit the earth
Sometimes size really does not matter: recent papers on the tumour necrosis factor (TNF)-like ligand, TWEAK (tumour necrosis… 
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