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TNFAIP3 gene

Known as: Tumor Necrosis Factor, Alpha-Induced Protein 3 Gene, OTU DOMAIN-CONTAINING PROTEIN 7C, OTUD7C 
This gene may play a role in the regulation of apoptosis.
National Institutes of Health

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Related topics

7 relations
ApoptosisDeubiquitinationTNFAIP2 geneTNFAIP3 protein, human

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TNFAIP3 wt Allele

Papers overview

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2018
2018
Association of ITGAM, TNFSF4, TNFAIP3 and STAT4 gene polymorphisms with risk of systemic lupus erythematosus in a North Indian population
Several susceptibility genes have been associated with systemic lupus erythematosus (SLE) across different populations worldwide… 
2017
2017
Upregulation of the C/EBP β LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus
Abstract Objectives: We aimed to examine CCAAT/enhancer-binding protein β (C/EBP β), TNF-alpha-induced protein 3 (TNFAIP3), and… 
2015
2015
The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity
Genome‐wide association studies in white and Chinese Han populations have found that the single‐nucleotide polymorphism (SNP… 
2015
2015
TNFAIP3 and IL12B gene polymorphisms associated with psoriasis vulgaris in an Egyptian cohort
Psoriasis vulgaris is a common chronic inflammatory skin disease. Development of early onset psoriasis is, to some extent… 
2014
2014
Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.
Tumor necrosis factor-induced protein 3 (TNFAIP3; also known as A20) negatively regulates NF-κB and MAPK signals to control… 
2013
2013
TNFAIP3 Gene Polymorphisms in a Chinese Han Population with Vogt–Koyanagi–Harada Syndrome
Background This study was performed to evaluate the potential association of TNFAIP3 polymorphisms with Vogt–Koyanagi–Harada (VKH… 
2012
2012
Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.
OBJECTIVE The aim of this study was to determine whether the tumor necrosis factor-alpha-inducible protein 3 (TNFAIP3… 
2011
2011
Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL
Chronic lymphocytic leukemia (CLL) cells show constitutive nuclear factor kappa B (NF‐κB) activation, which may have a… 
Highly Cited
2010
Highly Cited
2010
African-Derived Genetic Polymorphisms in TNFAIP3 Mediate Risk for Autoimmunity
The TNF α-induced protein 3 (TNFAIP3) is an ubiquitin-modifying enzyme and an essential negative regulator of inflammation… 
2010
2010
Association of TNFAIP3 Polymorphism with Susceptibility to Systemic Lupus Erythematosus in a Japanese Population
Recent genome-wide association studies demonstrated association of single nucleotide polymorphisms (SNPs) in the TNFAIP3 region… 
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