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TMC-95A

Known as: TMC 95A 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Cyclic Peptides

Papers overview

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2012
2012
Noncovalent inhibition of 20S proteasome by pegylated dimerized inhibitors.
Review
2010
Review
2010
Intermolecular oxidative cross-coupling of arenes.
Biaryls constitute an important subunit found in medicinal agents, functional materials, and natural products. While the Suzuki… 
Highly Cited
2007
Highly Cited
2007
Linear TMC-95-based proteasome inhibitors.
We have designed and evaluated 45 linear analogues of the natural constrained cyclopeptide TMC-95A. These synthetically less… 
2004
2004
A concise, total synthesis of the TMC-95A/B proteasome inhibitors.
A concise, total synthesis of the proteasome inhibitors TMC-95A/B has been accomplished. The synthesis features the use of an L… 
Highly Cited
2003
Highly Cited
2003
A concise formal total synthesis of TMC-95A/B proteasome inhibitors.
[reaction: see text] A formal total synthesis of proteasome inhibitors TMC-95A/B is described. The synthesis features a… 
2003
2003
Synthesis of macrocyclic peptide analogues of proteasome inhibitor TMC-95A.
The synthesis of three constrained macrocyclic peptide analogues 1 of TMC-95A as potential proteasome inhibitors is described… 
2003
2003
Simplified Synthetic TMC‐95A/B Analogues Retain the Potency of Proteasome Inhibitory Activity
The proteasome regulates diverse intracellular processes, including cell‐cycle progression, antigen presentation, and… 
Review
2002
Review
2002
The core structure of TMC-95A is a promising lead for reversible proteasome inhibition.
Correspondingly,great attention has recently been paid to the discovery ofpotentandselectiveproteasomeinhibitorsbystructure… 
Highly Cited
2002
Highly Cited
2002
The total synthesis of proteasome inhibitors TMC-95A and TMC-95B: discovery of a new method to generate cis-propenyl amides.
2001
2001
Stereocontrolled synthesis of the northern part of potent proteasome inhibitor TMC-95A.
[reaction: see text]. A protected version of the northern part of TMC-95A, a potent and selective proteasome inhibitor, was… 
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