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TM4SF1 gene

Known as: MEMBRANE COMPONENT, CHROMOSOME 3, SURFACE MARKER 1, TM4SF1, transmembrane 4 L six family member 1 
This gene plays a role in signal transduction events that are involved in cellular development, activation, growth and motility.
National Institutes of Health

Related topics

Related topics

2 relations
TM4SF1 protein, humanTM4SF1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
TM4SF1 involves in miR-1-3p/miR-214-5p-mediated inhibition of the migration and proliferation in keloid by regulating AKT/ERK signaling.
2019
2019
TM4SF1 is a potential target for anti-invasion and metastasis in ovarian cancer
Patients with ovarian cancer commonly have a poor prognosis, owing to its invasiveness and distant metastasis. Studies have found… 
2019
2019
TM4SF1, a binding protein of DVL2 in hepatocellular carcinoma, positively regulates beta‐catenin/TCF signalling
The interaction between Axin and DVL2 is critical for the breaking down of the beta‐catenin destruction complex and the… 
2018
2018
MiRNA-206 suppresses PGE2-induced colorectal cancer cell proliferation, migration, and invasion by targetting TM4SF1
MiRNA (miR)-206 plays a tumor suppressor role in various cancer types. Here, we investigated whether miR-206 is involved in… 
2017
2017
TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer… 
2017
2017
MicroRNA-30a-5p (miR-30a) regulates cell motility and EMT by directly targeting oncogenic TM4SF1 in colorectal cancer
PurposeColorectal cancer (CRC) is one of the leading causes of cancer death worldwide, and many oncogenes and tumor suppressor… 
Highly Cited
2016
Highly Cited
2016
MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer.
Transmembrane-4-L6 family 1 (TM4SF1) is upregulated in colorectal carcinoma (CRC). However, the mechanism leading to inhibition… 
2016
2016
TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141
Cancer stem-like cells have been identified in primary human tumors and cancer cell lines. Previously we found TM4SF1 gene was… 
Highly Cited
2013
Highly Cited
2013
New Insights into FoxE1 Functions: Identification of Direct FoxE1 Targets in Thyroid Cells
Background FoxE1 is a thyroid-specific forkhead transcription factor essential for thyroid gland development, as well as for the… 
Highly Cited
1998
Highly Cited
1998
Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain.
To determine the properties of the cAMP-specific, rolipram-sensitive phosphodiesterases (cAMP-PDEs) that are expressed in… 
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