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TLK-199

Known as: TER199, TLK 199, TLK199 
A liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity. After… 
National Institutes of Health

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Related topics

2 relations
Ezatiostat Hydrochloride

Narrower (1)

Telintra

Papers overview

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2011
2011
Phase 1 Dose-Ranging Study of Oral Ezatiostat Hydrochloride (Telintra®, TLK199) in Combination with Lenalidomide (Revlimid®) in Patients with Non-Deletion(5q) Low to Intermediate-1 Risk…
Abstract 2778 Introduction: Lenalidomide is approved for the treatment of del(5q) MDS in US and Japan. In Low to Intermediate-1… 
2011
2011
Gene Expression Studies May Identify Lower Risk Myelodysplastic Syndrome Patients Likely to Respond to Therapy with Ezatiostat Hydrochloride (TLK199)
Abstract 2779 Interpretation of gene expression studies in MDS have been especially challenging due to the heterogeneity of the… 
2010
2010
Oral Ezatiostat HCl (TLK199) and Myelodysplastic syndrome: A case report of sustained hematologic response following an abbreviated exposure
Treatment options for patients with lower risk non-del(5q) myelodysplastic syndromes (MDS) who fail erythroid stimulating agents… 
2008
2008
Induction of apoptosis by TLK199 in human leukemia cells
2270 TLK199 (ezatiostat hydrochloride) is a novel glutathione analog inhibitor of the enzyme glutathione S-transferase P1-1 (GST… 
2007
2007
Phase 1 Dose Escalation Study of TLK199 Tablets (Telintra), a Novel Glutathione Analog, in Myelodysplastic Syndrome.
Introduction: Glutathione S-transferase (GST) P1-1 binds to and inhibits Jun kinase (JNK), a key regulator of cellular… 
2006
2006
Telintra™ (TLK199) Enhances Granulocyte Colony-Stimulating Factor Production.
TLK199 is a novel glutathione analog inhibitor of the enzyme GST P1-1. GST P1-1 has been shown to be a negative regulator of c… 
2004
2004
Clinical trial news.
TelintraTM (TLK199) is a Novel Glutathione Inhibitor of GST P1-1. Telik scientists and academic collaborators reported… 
2003
2003
Resistance to phorbol 12-myristate 13-acetate-induced cell growth arrest in an HL60 cell line chronically exposed to a glutathione S-transferase pi inhibitor.
1997
1997
Laminin suppresses progesterone production by human luteinizing granulosa cells via interaction with integrin alpha 6 beta 1.
We previously raised a murine monoclonal antibody (mAb), OG-1, against human granulosa cells (GC) and reported that human GC… 
1963
1963
Prof. Dr. Werner Bavendamm 65 Jahre
  • H. Zycha
  • Holz als Roh- und Werkstoff
  • 1963
  • Corpus ID: 13191116
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