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Ezatiostat Hydrochloride

A liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity. After… Expand
National Institutes of Health

Papers overview

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Review
2020
Review
2020
Myelodysplastic syndrome (MDS) represents a heterogeneous group of clonal hematopoietic disorders, which is characterized by… Expand
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2019
2019
Perfluorooctane sulfonamide (FOSA) is known as a key intermediate of perfluorooctane sulfonic acid (PFOS) precursors, which can… Expand
Review
2015
Review
2015
Introduction: Myelodysplastic syndromes (MDSs) are associated with significant morbidity due to ineffective hematopoiesis. Given… Expand
2012
2012
BackgroundEzatiostat, a glutathione S-transferase P1-1 inhibitor, promotes the maturation of hematopoietic progenitors and… Expand
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2012
2012
BackgroundApproximately 70% of all patients with myelodysplastic syndrome (MDS) present with lower-risk disease. Some of these… Expand
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2011
2011
Abstract 2778 Introduction: Lenalidomide is approved for the treatment of del(5q) MDS in US and Japan. In Low to Intermediate-1… Expand
2011
2011
Abstract 2779 Interpretation of gene expression studies in MDS have been especially challenging due to the heterogeneity of the… Expand
2011
2011
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Ezatiostat hydrochloride (TLK199, Telintra®) is the… Expand
Highly Cited
2009
Highly Cited
2009
Phase 1 testing of ezatiostat, a glutathione S-transferase P1-1 inhibitor, for the treatment of myelodysplastic syndrome was… Expand
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2009
2009
BackgroundEzatiostat hydrochloride liposomes for injection, a glutathione S-transferase P1-1 inhibitor, was evaluated in… Expand
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