FAQ

THRB gene

Known as: Genes, TR beta, beta Genes, TR, THRB Genes 
This gene plays a role in receptor signaling and regulation of transcription. It is involved in inner ear development and color vision.

Topic mentions per year

Topic mentions per year

1983-2018
0102019832018

Related topics

Related topics

14 relations
Biologic DevelopmentCell Differentiation processCell ProliferationHomeostasis
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THRB wt Allele

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
THRB gene
Signal Transduction
Homeostasis
Cell Differentiation process
Cell Proliferation
dna binding

Papers overview

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Highly Cited
2004
Highly Cited
2004
Toxicity of glyphosate-based pesticides to four North American frog species.
Glyphosate-based herbicides are among the most widely used pesticides in the world. We compared the acute toxicity of the… (More)
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Highly Cited
2002
Highly Cited
2002
Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.
The molecular genetic basis of thyroid carcinogenesis is not well understood. Most of the existing models of thyroid cancer only… (More)
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Highly Cited
2001
Highly Cited
2001
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue.
Type 2 iodothyronine deiodinase (D2) is a selenoenzyme, the product of the recently cloned cAMP-dependent Dio2 gene, which… (More)
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Highly Cited
2001
Highly Cited
2001
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
Thyroid hormone receptors are encoded by the TRalpha (NR1A1) and TRbeta (NR1A2) loci. These genes are transcribed into multiple… (More)
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Highly Cited
2000
Highly Cited
2000
Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone.
Patients with mutations in the thyroid hormone receptor beta (TRbeta) gene manifest resistance to thyroid hormone (RTH… (More)
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Highly Cited
1999
Highly Cited
1999
Proteasome-dependent degradation of the human estrogen receptor.
In eukaryotic cells, the ubiquitin-proteasome pathway is the major mechanism for the targeted degradation of proteins with short… (More)
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Highly Cited
1995
Highly Cited
1995
Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study.
OBJECTIVE To determine the genetic and clinical features of resistance to thyroid hormone in a study from a single institution… (More)
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Highly Cited
1994
Highly Cited
1994
Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.
The cDNA for a member of the nuclear receptor family was cloned and named ubiquitous receptor (UR), since UR protein and mRNA are… (More)
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Highly Cited
1993
Highly Cited
1993
Thyroid hormone-induced gene expression program for amphibian tail resorption.
The changes in gene expression leading to tail resorption that are initiated by thyroid hormone (TH) were studied in Xenopus… (More)
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Highly Cited
1993
Highly Cited
1993
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.
The human thyroid hormone receptor beta (hTR beta) is capable of both transcriptional silencing and hormone-dependent activation… (More)
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