Skip to search formSkip to main contentSkip to account menu

THRB gene

Known as: Genes, TR beta, beta Genes, TR, THRB Genes 
This gene plays a role in receptor signaling and regulation of transcription. It is involved in inner ear development and color vision.
National Institutes of Health

Related topics

Related topics

15 relations
Biologic DevelopmentCell Differentiation processCell ProliferationHomeostasis

Narrower (1)

THRB wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Insight into the physiological actions of thyroid hormone receptors from genetically modified mice.
Thyroid hormones exert a range of developmental and physiological actions in all vertebrates. Serum concentrations of L-thyroxine… 
Highly Cited
2001
Highly Cited
2001
Genetic Analysis Reveals Different Functions for the Products of the Thyroid Hormone Receptor α Locus
ABSTRACT Thyroid hormone receptors are encoded by the TRα(NR1A1) and TRβ (NR1A2) loci. These genes are transcribed into multiple… 
Highly Cited
2000
Highly Cited
2000
Cloning and Characterization of Two Novel Thyroid Hormone Receptor β Isoforms
  • G. Williams
  • Molecular and Cellular Biology
  • 2000
  • Corpus ID: 40735143
ABSTRACT Thyroid hormone (T3) activates nuclear receptor transcription factors, encoded by the TRα (NR1A1) and TRβ (NR1A2) genes… 
Highly Cited
1999
Highly Cited
1999
Proteasome-dependent degradation of the human estrogen receptor.
In eukaryotic cells, the ubiquitin-proteasome pathway is the major mechanism for the targeted degradation of proteins with short… 
Highly Cited
1998
Highly Cited
1998
A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.
Highly Cited
1997
Highly Cited
1997
The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans
  • T. C. White
  • Antimicrobial agents and chemotherapy
  • 1997
  • Corpus ID: 2770989
Azole resistance in the pathogenic yeast Candida albicans is an emerging problem in the human immunodeficiency virus (HIV… 
Highly Cited
1993
Highly Cited
1993
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.
The human thyroid hormone receptor beta (hTR beta) is capable of both transcriptional silencing and hormone-dependent activation… 
Highly Cited
1993
Highly Cited
1993
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
BACKGROUND Attention deficit-hyperactivity disorder is a well-recognized psychiatric disorder of childhood. Its cause is unknown… 
Highly Cited
1991
Highly Cited
1991
Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain.
Genetic analysis in our laboratory of families with generalized thyroid hormone resistance (GTHR) has demonstrated tight linkage… 
Highly Cited
1990
Highly Cited
1990
Contrasting developmental and tissue‐specific expression of alpha and beta thyroid hormone receptor genes.
Thyroid hormones and their receptors (TRs) have critical functions in development. Here we show that a chicken TR beta cDNA clone… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License