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THRB gene
Known as:
Genes, TR beta
, beta Genes, TR
, THRB Genes
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This gene plays a role in receptor signaling and regulation of transcription. It is involved in inner ear development and color vision.
National Institutes of Health
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Related topics
Related topics
15 relations
Biologic Development
Cell Differentiation process
Cell Proliferation
Homeostasis
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THRB wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Insight into the physiological actions of thyroid hormone receptors from genetically modified mice.
P. O’Shea
,
G. Williams
The Journal of endocrinology
2002
Corpus ID: 8711064
Thyroid hormones exert a range of developmental and physiological actions in all vertebrates. Serum concentrations of L-thyroxine…
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Highly Cited
2001
Highly Cited
2001
Genetic Analysis Reveals Different Functions for the Products of the Thyroid Hormone Receptor α Locus
K. Gauthier
,
M. Plateroti
,
+10 authors
O. Chassande
Molecular and Cellular Biology
2001
Corpus ID: 16141181
ABSTRACT Thyroid hormone receptors are encoded by the TRα(NR1A1) and TRβ (NR1A2) loci. These genes are transcribed into multiple…
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Highly Cited
2000
Highly Cited
2000
Cloning and Characterization of Two Novel Thyroid Hormone Receptor β Isoforms
G. Williams
Molecular and Cellular Biology
2000
Corpus ID: 40735143
ABSTRACT Thyroid hormone (T3) activates nuclear receptor transcription factors, encoded by the TRα (NR1A1) and TRβ (NR1A2) genes…
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Highly Cited
1999
Highly Cited
1999
Proteasome-dependent degradation of the human estrogen receptor.
Z. Nawaz
,
D. Lonard
,
A. P. Dennis
,
C. Smith
,
B. O’Malley
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 23430241
In eukaryotic cells, the ubiquitin-proteasome pathway is the major mechanism for the targeted degradation of proteins with short…
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Highly Cited
1998
Highly Cited
1998
A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.
G. Chiellini
,
J. Apriletti
,
H. Yoshihara
,
J. Baxter
,
R. C. Ribeiro
,
T. Scanlan
Chemistry & biology
1998
Corpus ID: 34151117
Highly Cited
1997
Highly Cited
1997
The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans
T. C. White
Antimicrobial agents and chemotherapy
1997
Corpus ID: 2770989
Azole resistance in the pathogenic yeast Candida albicans is an emerging problem in the human immunodeficiency virus (HIV…
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Highly Cited
1993
Highly Cited
1993
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.
A. Baniahmad
,
I. Ha
,
D. Reinberg
,
S. Tsai
,
M. Tsai
,
B. O’Malley
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 20245917
The human thyroid hormone receptor beta (hTR beta) is capable of both transcriptional silencing and hormone-dependent activation…
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Highly Cited
1993
Highly Cited
1993
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
P. Hauser
,
A. Zametkin
,
+4 authors
B. Weintraub
The New England journal of medicine
1993
Corpus ID: 22196230
BACKGROUND Attention deficit-hyperactivity disorder is a well-recognized psychiatric disorder of childhood. Its cause is unknown…
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Highly Cited
1991
Highly Cited
1991
Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain.
R. Parrilla
,
A. J. Mixson
,
J. McPherson
,
J. Mcclaskey
,
B. Weintraub
The Journal of clinical investigation
1991
Corpus ID: 11184686
Genetic analysis in our laboratory of families with generalized thyroid hormone resistance (GTHR) has demonstrated tight linkage…
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Highly Cited
1990
Highly Cited
1990
Contrasting developmental and tissue‐specific expression of alpha and beta thyroid hormone receptor genes.
D. Forrest
,
M. Sjöberg
,
B. Vennström
The EMBO journal
1990
Corpus ID: 32040737
Thyroid hormones and their receptors (TRs) have critical functions in development. Here we show that a chicken TR beta cDNA clone…
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