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THK5351

National Institutes of Health

Papers overview

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2019
2019
BackgroundTHK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target… Expand
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2018
2018
Background: Imaging studies in Alzheimer’s disease (AD) have yet to answer the underlying questions concerning the relationship… Expand
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2018
2018
PurposeWe investigated the regional distribution of 18F-THK5351 uptake in gray (GM) and white matter (WM) in patients with… Expand
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2018
2018
PurposeOff-target binding in the reference region is a challenge for recent tau tracers 18F-AV-1451 and 18F-THK5351. The… Expand
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2018
2018
Recent positron emission tomography (PET) studies have demonstrated the accumulation of tau PET tracer in the affected region of… Expand
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2017
2017
BackgroundThe aim of this study was to compare the binding properties of several tau positron emission tomography tracers—THK5117… Expand
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2017
2017
  • Y. Jang, C. Lyoo, +14 authors S. Seo
  • European Journal of Nuclear Medicine and…
  • 2017
  • Corpus ID: 9321194
PurposeTau accumulation is a core pathologic change in various neurodegenerative diseases including Alzheimer’s disease and… Expand
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2017
2017
The radiotracer, [18 F]-THK-5351, is a highly selective and high-binding affinity PET imaging agent for aggregates of hyper… Expand
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Highly Cited
2016
Highly Cited
2016
Imaging of neurofibrillary pathology in the brain helps in diagnosing dementia, tracking disease progression, and evaluating the… Expand
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2016
2016
Purpose18F-THK5351 is a novel radiotracer developed for in vivo imaging of tau pathology in the brain. For the quantitative… Expand
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