THK5351

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2016-2018
012320162018

Papers overview

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2018
2018
Off-target binding in the reference region is a challenge for recent tau tracers 18F-AV-1451 and 18F-THK5351. The conventional… (More)
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2018
2018
BACKGROUND Semantic variant primary progressive aphasia (svPPA) has been associated with a variety of proteinopathies, mainly… (More)
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2017
2017
18F-THK5351 is a quinoline-derived tau imaging agent with high affinity to paired helical filaments (PHF). However, high levels… (More)
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2017
2017
Tau accumulation is a core pathologic change in various neurodegenerative diseases including Alzheimer’s disease and… (More)
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2017
2017
The aim of this study was to compare the binding properties of several tau positron emission tomography tracers—THK5117, THK5351… (More)
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Review
2017
Review
2017
Abnormal aggregation of tau in the brain is a major contributing factor in various neurodegenerative diseases. The role of tau… (More)
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2017
2017
This study aims to evaluate the clinical validity of [18F]THK5351 positron emission tomography (PET) for the assessment of… (More)
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2016
2016
UNLABELLED Imaging of neurofibrillary pathology in the brain helps in diagnosing dementia, tracking disease progression, and… (More)
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2016
2016
18F-THK5351 is a novel radiotracer developed for in vivo imaging of tau pathology in the brain. For the quantitative assessment… (More)
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2016
2016
BACKGROUND [18F]THK5351, a recently-developed positron emission tomography (PET) tracer for measuring tau neurofibrillary tangle… (More)
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