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THBS1 wt Allele

Known as: TSP1, Thrombospondin-1 Gene, TSP 
Human THBS1 wild-type allele is located in the vicinity of 15q15 and is approximately 16 kb in length. This allele, which encodes thrombospondin-1… 
National Institutes of Health

Related topics

Related topics

11 relations
15q15Angiogenic ProcessCell-Cell Adhesion ProcessCell-Matrix Junction

Broader (1)

THBS1 gene

Papers overview

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2011
2011
A Novel Transcriptional Mechanism of Cell Type–Specific Regulation of Vascular Gene Expression by Glucose
Objective—Vascular diabetic complications are associated with abnormal extracellular matrix and dysfunction of vascular cells… 
Highly Cited
2008
Highly Cited
2008
Aryl Hydrocarbon Receptor is Activated by High Glucose and Regulates the Thrombospondin‐1 Gene Promoter in Endothelial Cells
Glucose levels correlate directly with the diabetic vascular complications, and the earliest sign of vascular complications is… 
2008
2008
CCAAT box is required for the induction of human thrombospondin‐1 gene by trichostatin A
Histone deacetylase (HDAC) inhibitors have been reported to inhibit angiogenesis as well as tumor growth. Thrombospondin‐1 (TSP1… 
Highly Cited
2006
Highly Cited
2006
Epigenetic silencing of multiple genes in primary CNS lymphoma
Epigenetic silencing of functionally important genes is important in the development of malignancies and is a source of potential… 
Highly Cited
2005
Highly Cited
2005
Systemic administration of attenuated Salmonella choleraesuis carrying thrombospondin-1 gene leads to tumor-specific transgene expression, delayed tumor growth and prolonged survival in the murine…
Some anaerobic and facultative anaerobic bacteria have been used experimentally as anticancer agents because of their selective… 
2004
2004
Intelligence and individual differences in performance on three types of visually presented optimisation problems
Highly Cited
2003
Highly Cited
2003
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.
Tumor angiogenesis, a major requirement for tumor outgrowth and metastasis, is regulated by pro- and antiangiogenic factors… 
1995
1995
Characterization of humoral and cellular immunity in the central nervous system of HAM/TSP
Highly Cited
1992
Highly Cited
1992
Frequent clonal proliferation of human T-cell leukemia virus type 1 (HTLV-1)-infected T cells in HTLV-1-associated myelopathy (HAM-TSP).
Human T-cell leukemia virus type 1 (HTLV-1) integrates its proviruses into random sites in host chromosomal DNA. Random… 
1983
1983
[Experimental studies on distribution of cefotiam, a new beta-lactam antibiotic, in the lung and trachea of rabbits. II. Combined effects with serratiopeptidase].
Plasma levels and distribution in pulmonary and bronchial tissues of CTM following injection into the jugular vein were… 
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