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THBS1 gene

Known as: TSP1, Thrombospondin 1 Gene, thrombospondin-1p180 
This gene plays a role in the mediation of both intercellular and cell-matrix interactions. It is also involved in platelet aggregation and… 
National Institutes of Health

Related topics

Related topics

8 relations
Angiogenic ProcessCell-Cell Adhesion ProcessCell-Matrix JunctionThrombospondin 1

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THBS1 wt Allele

Papers overview

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2012
2012
Overexpression of thrombospondin‐1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma
The roles of thrombospondin‐1 (THBS‐1) in tumor growth and metastasis are complicated and its function as a cancer inhibitor or… 
2009
2009
Gene expression profile towards the prediction of patient survival of gastric cancer.
Highly Cited
2006
Highly Cited
2006
Differential Expression of Profibrotic and Growth Factors in Chronic Allograft Nephropathy
Background. Chronic allograft nephropathy (CAN) is a multifactorial process, where both immunological and nonimmunological… 
2004
2004
Shift in the Balance between Circulating Thrombospondin-1 and Vascular Endothelial Growth Factor in Cancer Patients: Relationship to Platelet α-Granule Content and Primary Activation
Tumoral angiogenesis is regulated by the balance between factors that activate and inhibit angiogenesis. Elevated levels of… 
Highly Cited
2003
Highly Cited
2003
Regulation of multiple tumor microenvironment markers by overexpression of single or paired combinations of ErbB receptors.
The progression of primary tumors to an invasive phenotype requires dynamic changes in multiple cellular and local tumor… 
Highly Cited
2003
Highly Cited
2003
Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma.
PURPOSE This study was designed to determine whether there is a methylator phenotype in stage I and II endometrioid endometrial… 
Highly Cited
2000
Highly Cited
2000
Inhibition of retinal angiogenesis by peptides derived from thrombospondin-1.
PURPOSE Thrombospondin (TSP)1 is a tumor suppressor with activity that is associated with its ability to inhibit… 
1999
1999
Age-Related Expression of Renal Thrombospondin 1 mRNA in F344 Rats: Resemblance to Diabetes-Induced Expression in Obese Zucker Rats
Age-related increases occurred in renal thrombospondin 1 (TSP1) mRNA in F344 rats, resembling diabetes-induced TSP1 mRNA in the… 
1997
1997
Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene (THBS2).
1990
1990
Structure and chromosomal localization of the human thrombospondin gene.
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