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TGFB1-Induced Anti-Apoptotic Factor 1

Known as: 12 kDa TGF-Beta-1-Induced Antiapoptotic Factor, TGF-Beta-1-Induced Antiapoptotic Factor 1 
TGFB1-induced anti-apoptotic factor 1 (115 aa, ~12 kDa) is encoded by the human TIAF1 gene. This protein plays a role in the modulation of apoptosis.
National Institutes of Health

Papers overview

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2012
2012
Anti-apoptotic Bfl-1 and pro-apoptotic Bax, two members of the Bcl-2 family sharing a similar structural fold, are classically… Expand
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2012
2012
The proteasome inhibitor bortezomib has shown remarkable clinical success in the treatment of multiple myeloma. However, the… Expand
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Highly Cited
2010
Highly Cited
2010
p73, the structural and functional homologue of p53, exists as two major forms: the transactivation-proficient, proapoptotic… Expand
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Highly Cited
2008
Highly Cited
2008
Background Ventricular remodeling in type 2 diabetes predisposes to fatal coronary heart disease. The proapoptotic forkhead class… Expand
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Highly Cited
2004
Highly Cited
2004
Reactive oxygen species (ROS) are important mediators for several biologic responses, including apoptosis. The present study… Expand
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Highly Cited
2004
Highly Cited
2004
Glucocorticoids promote thymocyte apoptosis and modulate transcription of numerous genes. GILZ (glucocorticoid-induced leucine… Expand
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Highly Cited
2002
Highly Cited
2002
Survivin is an inhibitor of apoptosis protein (IAP) that is markedly overexpressed in most cancers. We identified two novel… Expand
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1999
1999
The tremendous progress, which has been made in the study of cellular and molecular basis of the maturation and functioning of… Expand
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