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TGFB1-Induced Anti-Apoptotic Factor 1
Known as:
12 kDa TGF-Beta-1-Induced Antiapoptotic Factor
, TGF-Beta-1-Induced Antiapoptotic Factor 1
TGFB1-induced anti-apoptotic factor 1 (115 aa, ~12 kDa) is encoded by the human TIAF1 gene. This protein plays a role in the modulation of apoptosis.
National Institutes of Health
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Related topics
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6 relations
Apoptosis
Apoptosis Inhibitor
Genes, Regulator
Negative Regulation of Apoptosis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
µ-Calpain Conversion of Antiapoptotic Bfl-1 (BCL2A1) into a Prodeath Factor Reveals Two Distinct alpha-Helices Inducing Mitochondria-Mediated Apoptosis
J. G. Valero
,
Aurélie Cornut-Thibaut
,
+8 authors
J. Kucharczak
PLoS ONE
2012
Corpus ID: 7245602
Anti-apoptotic Bfl-1 and pro-apoptotic Bax, two members of the Bcl-2 family sharing a similar structural fold, are classically…
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Highly Cited
2012
Highly Cited
2012
The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4
Y. Zang
,
S. Thomas
,
+6 authors
Daniel E. Johnson
Autophagy
2012
Corpus ID: 30994680
The proteasome inhibitor bortezomib has shown remarkable clinical success in the treatment of multiple myeloma. However, the…
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Highly Cited
2010
Highly Cited
2010
The antiapoptotic DeltaNp73 is degraded in a c-Jun–dependent manner upon genotoxic stress through the antizyme-mediated pathway
I. Dulloo
,
G. Gopalan
,
G. Melino
,
K. Sabapathy
Proceedings of the National Academy of Sciences
2010
Corpus ID: 11010219
p73, the structural and functional homologue of p53, exists as two major forms: the transactivation-proficient, proapoptotic…
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Highly Cited
2008
Highly Cited
2008
Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat
E. Vahtola
,
M. Louhelainen
,
+6 authors
E. Mervaala
Journal of Hypertension
2008
Corpus ID: 11110098
Background Ventricular remodeling in type 2 diabetes predisposes to fatal coronary heart disease. The proapoptotic forkhead class…
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Highly Cited
2004
Highly Cited
2004
Oxidative stress mediates apoptotic changes induced by hyperglycemia in human tubular kidney cells.
D. Verzola
,
M. Bertolotto
,
+7 authors
G. Deferrari
Journal of the American Society of Nephrology
2004
Corpus ID: 33369768
Reactive oxygen species (ROS) are important mediators for several biologic responses, including apoptosis. The present study…
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Highly Cited
2004
Highly Cited
2004
Decrease of Bcl-xL and augmentation of thymocyte apoptosis in GILZ overexpressing transgenic mice.
D. Delfino
,
M. Agostini
,
S. Spinicelli
,
P. Vito
,
C. Riccardi
Blood
2004
Corpus ID: 20431309
Glucocorticoids promote thymocyte apoptosis and modulate transcription of numerous genes. GILZ (glucocorticoid-induced leucine…
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Highly Cited
2002
Highly Cited
2002
Differential subcellular localization of functionally divergent survivin splice variants
C. Mahotka
,
J. Liebmann
,
+4 authors
C. Gerharz
Cell Death and Differentiation
2002
Corpus ID: 7258625
Survivin is an inhibitor of apoptosis protein (IAP) that is markedly overexpressed in most cancers. We identified two novel…
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