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TGFB1-Induced Anti-Apoptotic Factor 1

Known as: 12 kDa TGF-Beta-1-Induced Antiapoptotic Factor, TGF-Beta-1-Induced Antiapoptotic Factor 1 
TGFB1-induced anti-apoptotic factor 1 (115 aa, ~12 kDa) is encoded by the human TIAF1 gene. This protein plays a role in the modulation of apoptosis.
National Institutes of Health

Papers overview

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2012
2012
Anti-apoptotic Bfl-1 and pro-apoptotic Bax, two members of the Bcl-2 family sharing a similar structural fold, are classically… Expand
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Highly Cited
2012
Highly Cited
2012
The proteasome inhibitor bortezomib has shown remarkable clinical success in the treatment of multiple myeloma. However, the… Expand
Highly Cited
2010
Highly Cited
2010
p73, the structural and functional homologue of p53, exists as two major forms: the transactivation-proficient, proapoptotic… Expand
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Highly Cited
2008
Highly Cited
2008
Background Ventricular remodeling in type 2 diabetes predisposes to fatal coronary heart disease. The proapoptotic forkhead class… Expand
Highly Cited
2004
Highly Cited
2004
Reactive oxygen species (ROS) are important mediators for several biologic responses, including apoptosis. The present study… Expand
Highly Cited
2004
Highly Cited
2004
Glucocorticoids promote thymocyte apoptosis and modulate transcription of numerous genes. GILZ (glucocorticoid-induced leucine… Expand
Highly Cited
2002
Highly Cited
2002
Survivin is an inhibitor of apoptosis protein (IAP) that is markedly overexpressed in most cancers. We identified two novel… Expand
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