TGF beta type III receptor

Known as: Transforming Growth Factor Beta Receptor Type 3, TGFR-3, receptor, TGF-beta type III 
Transforming growth factor beta receptor type 3 (851 aa, ~93 kDa) is encoded by the human TGFBR3 gene. This protein is involved in TGF-beta binding.
National Institutes of Health

Related topics

Related topics

18 relations
ALK PathwayCTCF PathwayEnzyme GeneLigand Binding
(More)

Broader (2)

ProteoglycanTransforming Growth Factor beta Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Roles for the type III TGF-beta receptor in human cancer.
Transforming growth factor beta (TGF-beta) superfamily ligands have important roles in regulating cellular homeostasis, embryonic… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor.
The bone morphogenetic protein (BMP) family, the largest subfamily of the structurally conserved transforming growth factor-beta… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The type III TGF-beta receptor suppresses breast cancer progression.
The TGF-beta signaling pathway has a complex role in regulating mammary carcinogenesis. Here we demonstrate that the type III TGF… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer.
The transforming growth factor-beta (TGF-beta) signaling pathway has an important role in regulating normal prostate epithelium… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Endoglin modulates cellular responses to TGF-beta 1
Endoglin is a homodimeric membrane glycoprotein which can bind the beta 1 and beta 3 isoforms of transforming growth factor-beta… (More)
  • figure 1
  • figure 2
  • figure 4
  • table 1
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites
Betaglycan, also known as the TGF-beta type III receptor, is a membrane-anchored proteoglycan that presents TGF-beta to the type… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Betaglycan presents ligand to the TGF beta signaling receptor.
Transforming growth factor beta (TGF beta) signals through a heteromeric protein kinase receptor that has a limited ability to… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
A large domain common to sperm receptors (Zp2 and Zp3) and TGF-beta type III receptor.
A new family of mosaic proteins is defined by sequence analysis. The family is characterized by a 260 residue domain common to… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.
Endoglin, a dimeric membrane glycoprotein expressed at high levels on human vascular endothelial cells, shares regions of… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system.
We describe the primary structure of rat betaglycan, a polymorphic membrane-anchored proteoglycan with high affinity for… (More)
Is this relevant?