TFRC gene

Known as: TFR, TRANSFERRIN RECEPTOR 1, TFRC 
This gene plays a regulatory role in receptor-mediated endocytosis and iron metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2018
010203019752018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Monoclonal antibodies have therapeutic potential for treating diseases of the central nervous system, but their accumulation in… (More)
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Highly Cited
2007
Highly Cited
2007
At least five arenaviruses cause viral haemorrhagic fevers in humans. Lassa virus, an Old World arenavirus, uses the cellular… (More)
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Highly Cited
2007
Highly Cited
2007
Inherited microcytic-hypochromic anemias in rodents and zebrafish suggest the existence of corresponding human disorders. The… (More)
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Highly Cited
2003
Highly Cited
2003
Under chronic inflammatory conditions cytokines induce a diversion of iron traffic, leading to hypoferremia and retention of the… (More)
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Highly Cited
2002
Highly Cited
2002
To perform vectorial secretory and transport functions that are critical for the survival of the organism, epithelial cells sort… (More)
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Highly Cited
2000
Highly Cited
2000
HFE is related to major histocompatibility complex (MHC) class I proteins and is mutated in the iron-overload disease hereditary… (More)
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Highly Cited
1999
Highly Cited
1999
Expression of the transferrin receptor, which mediates iron uptake from transferrin, is negatively regulated post… (More)
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Highly Cited
1998
Highly Cited
1998
We recently reported the positional cloning of a candidate gene for hereditary hemochromatosis called HFE. The gene product, a… (More)
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Highly Cited
1987
Highly Cited
1987
Initiation of T-lymphocyte proliferation by mitogen or antigen involves a cascade of gene activation events. Thus, by the time… (More)
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Highly Cited
1975
Highly Cited
1975
The objective of the study was to evaluate the diagnostic efficiency of laboratory tests, including serum transferrin receptor… (More)
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