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TERF2IP wt Allele

Known as: PP8000, RAP1, RAP1, Yeast, Homolog Gene 
Human TERF2IP wild-type allele is located in the vicinity of 16q23.1 and is approximately 113 kb in length. This allele, which encodes telomeric… 
National Institutes of Health

Related topics

Related topics

3 relations
16q23.1Telomere MaintenanceTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Rap1 prevents telomere fusions by nonhomologous end joining
Telomeres protect chromosomes from end‐to‐end fusions. In yeast Saccharomyces cerevisiae, the protein Rap1 directly binds… 
Review
2003
Review
2003
Does Rap1 deserve a bad Rap?
Highly Cited
2000
Highly Cited
2000
Sequential Regulation of the Small GTPase Rap1 in Human Platelets
ABSTRACT Rap1, a small GTPase of the Ras family, is ubiquitously expressed and particularly abundant in platelets. Previously we… 
Review
1998
Review
1998
All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral
Ras, Rap1 and Ral are related small GTPases. While the function of Ras in signal transduction is well established, it has been… 
Highly Cited
1997
Highly Cited
1997
From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
Highly Cited
1995
Highly Cited
1995
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing
The Silent Information Regulatory proteins, Sir3 and Sir4, and the telomeric repeat-binding protein RAP1 are required for the… 
Highly Cited
1994
Highly Cited
1994
The yeast telomere‐binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.
The protein RAP1 is essential for the maintenance of the telomeres of Saccharomyces cerevisiae and binds in vitro to multiple… 
Highly Cited
1991
Highly Cited
1991
Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.
The repressor/activator protein 1 (RAP1) binds to the upstream activating sites of many genes, the silencer elements flanking the… 
Highly Cited
1990
Highly Cited
1990
RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
Highly Cited
1987
Highly Cited
1987
Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements
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