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TERF2IP wt Allele

Known as: PP8000, RAP1, RAP1, Yeast, Homolog Gene 
Human TERF2IP wild-type allele is located in the vicinity of 16q23.1 and is approximately 113 kb in length. This allele, which encodes telomeric… 
National Institutes of Health

Related topics

Related topics

3 relations
16q23.1Telomere MaintenanceTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Mutant Telomeric Repeats in Yeast Can Disrupt the Negative Regulation of Recombination-Mediated Telomere Maintenance and Create an Alternative Lengthening of Telomeres-Like Phenotype
ABSTRACT Some human cancers maintain telomeres using alternative lengthening of telomeres (ALT), a process thought to be due to… 
2008
2008
Effects of prostaglandin E2 on the subcellular localization of Epac-1 and Rap1 proteins during Fcgamma-receptor-mediated phagocytosis in alveolar macrophages.
Highly Cited
2007
Highly Cited
2007
Telomere Loops and Homologous Recombination-Dependent Telomeric Circles in a Kluyveromyces lactis Telomere Mutant Strain
ABSTRACT The Kluyveromyces lactis ter1-16T strain contains mutant telomeres that are poorly bound by Rap1, resulting in a… 
2005
2005
Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac
Rap1 is a Ras-related GTPase that is principally involved in integrin- and E-cadherin-mediated adhesion. Rap1 is transiently… 
2004
2004
Genetic Dissection of the Kluyveromyces lactis Telomere and Evidence for Telomere Capping Defects in TER1 Mutants with Long Telomeres
ABSTRACT In the yeast Kluyveromyces lactis, the telomeres are composed of perfect 25-bp repeats copied from a 30-nucleotide RNA… 
2003
2003
Rap1 reverses transcriptional repression of TGF‐β type II receptor by a mechanism involving AP‐1 in the human pancreatic cancer cell line, UK Pan‐1
The TGF‐β signaling pathway has potent anti‐mitogenic effects in epithelial cells and loss of negative growth regulation is often… 
1997
1997
Immunolocalization of Rap1 in the Rat Parotid Gland: Detection on Secretory Granule Membranes
The objective of this study was to localize rap1 in the rat parotid gland. Rap1 is a small GTP-binding protein that has been… 
1994
1994
RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions.
Repressor Activator Protein 1 (RAP1) of Saccharomyces cerevisiae is an abundant nuclear protein implicated in telomere length… 
1990
1990
Phosphorylation influences the binding of the yeast RAP1 protein to the upstream activating sequence of the PGK gene.
Yeast repressor activator protein 1 (RAP1) binds in vitro to specific DNA sequences that are found in diverse genetic elements… 
1990
1990
Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins
Normal human rap1A and 35A rap1A (which encodes a protein with a Thr-35----Ala mutation) were cloned into a baculovirus transfer… 
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