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TDGF1 gene

Known as: TDGF1, CRGF, Cripto-1 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Genes
TDGF1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Human Cripto-1 overexpression in the mouse mammary gland results in the development of hyperplasia and adenocarcinoma
Human Cripto-1 (CR-1) is overexpressed in approximately 80% of human breast, colon and lung carcinomas. Mouse Cr-1 upregulation… 
Review
2002
Review
2002
Cripto: A tumor growth factor and more
Cripto, a growth factor with an EGF‐like domain, and the first member of the EGF‐CFC family of genes to be sequenced and… 
Highly Cited
2001
Highly Cited
2001
Cripto-1 enhances migration and branching morphogenesis of mouse mammary epithelial cells.
Cripto-1 is an EGF-CFC protein that performs an important role during early vertebrate development and is overexpressed in… 
Review
2000
Review
2000
The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.
The EGF-CFC gene family encodes a group of structurally related proteins that serve as important competence factors during early… 
Highly Cited
1999
Highly Cited
1999
Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells.
Cripto-1 (CR-1), a member of the epidermal growth factor-CFC peptide family, activates the ras/raf/mitogen-activated protein… 
Highly Cited
1996
Highly Cited
1996
Differential immunohistochemical detection of transforming growth factor α, amphiregulin and CRIPTO in human normal and malignant breast tissues
The expression of growth factors, such as transforming growth factor α (TGFα), amphiregulin (AR) and CRIPTO, a type‐1 tyrosine… 
Highly Cited
1996
Highly Cited
1996
Detection of amphiregulin and Cripto‐1 in mammary tumors from transgenic mice
Epidermal growth factor family members are widely expressed in human breast cancer and are thought to play an important dual role… 
Highly Cited
1995
Highly Cited
1995
Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas
The expression of amphiregulin (AR), heregulin (HRG), and cripto-1 (CR-1) mRNA transcripts was assessed in 60 human primary… 
Highly Cited
1993
Highly Cited
1993
Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells.
Carcinogenesis requires a complex series of genetic changes often involving multiple oncogenes and the inactivation of multiple… 
Highly Cited
1991
Highly Cited
1991
Expression of cripto, a novel gene of the epidermal growth factor gene family, leads to in vitro transformation of a normal mouse mammary epithelial cell line.
cripto is a gene encoding an epidermal growth factor-related protein that is expressed in undifferentiated embryonal carcinoma… 
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