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TCF3 gene

Known as: transcription factor E2-alpha, VDR interacting repressor, kappa-E2-binding factor 
This gene plays a role in regulation of transcription. It is involved in the control of tissue-specific cell fate during embryogenesis.
National Institutes of Health

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Related topics

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Cell Fate ControlHomo sapiensTranscription Factor 3Transcriptional Regulation

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TCF3 wt Allele

Papers overview

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Highly Cited
2009
Highly Cited
2009
Investigation of the Effect of Various Fluoride Compounds and Preparations Thereof on Erosive Tissue Loss in Enamel in vitro
Metal fluoride preparations are promising in view of protection against dental erosion. The aim of this study was to screen the… 
Highly Cited
2002
Highly Cited
2002
Gradient of E2A Activity in B-Cell Development
ABSTRACT The E2A locus is a frequent target of chromosomal translocations in B-cell acute lymphoblastic leukemia (B-ALL). E2A… 
Highly Cited
2002
Highly Cited
2002
Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system
The transcription factors encoded by the E2A gene are known to be essential for B lymphocyte development, and ectopic expression… 
Highly Cited
2001
Highly Cited
2001
Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction.
1997
1997
The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and Class I Hox proteins…
Oncoprotein E2a-Pbx1 contains the N-terminal transactivation domains of E2a and the majority of the homeodomain protein, Pbx1… 
Highly Cited
1994
Highly Cited
1994
The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation.
The immunoglobulin enhancer-binding proteins, E12 and E47, encoded by the E2A gene belong to the basic helix-loop-helix (bHLH… 
Highly Cited
1993
Highly Cited
1993
Localization of E2A mRNA expression in developing and adult rat tissues.
E2A helix-loop-helix proteins are involved in the control of various developmental pathways. We show here by in situ… 
Highly Cited
1993
Highly Cited
1993
E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development
A monoclonal antibody (Yae) was characterized and shown to specifically recognize E2A proteins in vivo, including the E2A-Pbx1… 
Highly Cited
1990
Highly Cited
1990
Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter.
Highly Cited
1983
Highly Cited
1983
E1A control of gene expression is mediated by sequences 5' to the transcriptional starts of the early viral genes
A product of the adenovirus E1A gene is a positive regulator of early viral gene expression. In this report we show that E1A… 
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