Transcription Factor 3

Known as: Class B Basic Helix-Loop-Helix Protein 21, Transcription Factor E2-Alpha, Kappa-E2-Binding Factor 
A basic helix-loop-helix transcription factor that plays a role in determining cell fate during embryogenesis. It forms a heterodimer with TWIST… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2018
0102019832018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
It is now established that the transcription factors E2A, EBF1 and Foxo1 have critical roles in B cell development. Here we show… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The dual function of stem cells requires them not only to form new stem cells through self-renewal but also to form lineage… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The role of specific transcription factors in the initiation and regulation of Ig gene rearrangements has been studied… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Beta-catenin-dependent or canonical Wnt signals are fundamental in animal development and tumor progression. Using Xenopus laevis… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The generation of B lymphocyte precursors is dependent on the combinatorial action of the transcription factors PU.1, Ikaros, E2A… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The E2A-HLF fusion gene transforms human pro-B lymphocytes by interfering with an early step in apoptotic signaling. In a search… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The transcription factors EBF and E2A are required at a similar step in early B cell differentiation. EBF and E2A synergistically… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Heterodimers between tissue-specific basic-helix-loop-helix proteins and the gene products of E2A play major roles in determining… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
A t(17;19) chromosomal translocation in early B-lineage acute leukemia was shown to result in chimeric transcripts that contain… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
The gene (E2A) for enhancer binding transcription factors E12 and E47 maps to the t(1;19) chromosomal translocation breakpoint in… (More)
Is this relevant?