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TC 81
Known as:
3,5-Pyridinedicarboxylic acid, 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-, 2,2-dimethyl-3-(methyl(phenylmethyl)amino)propyl methyl ester, monohydrochloride
, TC-81
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Dihydropyridines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
[Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery].
Y. Okamiya
,
T. Kishimoto
,
K. Aoki
,
K. Sunakawa
,
K. Hoshina
,
T. Takeshita
Nihon yakurigaku zasshi. Folia pharmacologica…
1993
Corpus ID: 12758115
The effects of palonidipine hydrochloride [TC-81: (+/-)-3-benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl…
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1993
1993
[Effect of palonidipine hydrochloride (TC-81), a new dihydropyridine derivative, on various myocardial ischemic models].
T. Kishimoto
,
Y. Okamiya
,
K. Aoki
,
M. Ota
,
K. Hoshina
,
T. Takeshita
Nihon yakurigaku zasshi. Folia pharmacologica…
1993
Corpus ID: 22971850
The antianginal effects of palonidipine, a novel 1,4-dihydropyridine derivative, and nifedipine on various myocardial ischemic…
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1993
1993
[Inhibitory effects of palonidipine hydrochloride (TC-81) on contractions induced by various vasoconstrictors in rat aorta].
K. Aoki
,
T. Kishimoto
,
K. Sunakawa
,
Y. Okamiya
,
K. Hoshina
,
T. Takeshita
Nihon yakurigaku zasshi. Folia pharmacologica…
1993
Corpus ID: 19214944
Inhibitions by palonidipine hydrochloride (TC-81), a new Ca entry blocker, of the contractile responses to norepinephrine (NE…
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1992
1992
Differences in Responses to TC-81 Among Various Arteries in Dogs
T. Kishimoto
,
K. Sunakawa
,
K. Aoki
,
Y. Okamiya
,
T. Takeshita
Journal of Cardiovascular Pharmacology
1992
Corpus ID: 41095939
Summary: The vasodilation induced by TC-81 was investigated in vitro and in vivo. In helical strips of dog arteries precontracted…
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1992
1992
Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo…
Y. Okamiya
,
T. Kishimoto
,
+4 authors
T. Naruchi
Arzneimittel-Forschung
1992
Corpus ID: 20609035
The antihypertensive effect of TC-81 ((+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro…
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1992
1992
Relationship between tissue content of TC-81 and relaxation of rat aorta.
Y. Okamiya
,
T. Kishimoto
,
K. Aoki
,
H. Tanabe
,
T. Takeshita
European Journal of Pharmacology
1992
Corpus ID: 23136288
1992
1992
Antihypertensive effect of the new calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl-methyl-4-(2-fluoro-5- nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate hydrochloride…
Y. Okamiya
,
T. Kishimoto
,
+4 authors
T. Naruchi
Arzneimittel-Forschung
1992
Corpus ID: 45145207
The antihypertensive effect of TC-81 ((+-)-3-(benzylmethylamino)-2,2-dimethylpropyl-methyl-4-(2-f luoro-5- nitrophenyl)-1,4…
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1992
1992
Absorption, plasma concentration, and excretion after single administration of 14C-(+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5- nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5…
T. Matsunaga
,
H. Tanabe
,
+7 authors
M. Kiyoki
Arzneimittel-Forschung
1992
Corpus ID: 10260243
The absorption, plasma concentrations, and excretion of a newly synthesized calcium antagonist, TC-81 ((+-)-3-(benzylmethylamino…
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1992
1992
Distribution to and elimination from tissues following a single or repeated administration of 14C-(+-)-3-(benzyl-methylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6…
T. Matsunaga
,
H. Tanabe
,
+5 authors
T. Takeshita
Arzneimittel-Forschung
1992
Corpus ID: 8663131
A newly synthesized calcium antagonist, TC-81((+-)-3-benzylmethylamino)-2,2-dimethylpropyl methyl-4-(2-fluoro-5-nitrophenyl)-1,4…
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1991
1991
Effect of TC-81, a new dihydropyridine derivative, on K+-induced contraction in rat aorta
Okamiya Yoshiaki
,
Kishimoto Tadashi
,
Aoki Kumiko
,
Tanabe Hirohumi
,
T. Toru
,
Naruchi Tatsuyuki
1991
Corpus ID: 84223315
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