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Anti-arthritic and immunoregulatory effects of TI-31 on collagen-induced arthritis.
TLDR
The results suggest that TI-31 depresses CIA by regulating the immune response to collagen through a mechanism different from that of anti-inflammatory drugs or immunosuppressants.
Vitamin D3 metabolites and PTH synergistically stimulate bone formation of chick embryonic femur in vitro
TLDR
Examination of the effects of vitamin D3 metabolites and PTH on bone formation in vitro reports that combinations of those metabolites, especially 1α,25-(OH)2D3 and 24R,25-3D3, directly stimulate calcification on bone synergistically with PTH.
Metabolites of feprazone in man.
TLDR
Two male volunteers received 400 mg of nonlabeled feprazone, 1,2-diphenyl-3,5-dioxo-4-(3'-methyl-but-2'-enyl)pyrazolidine and found that it belongs to a novel type of conjugate, (C)-beta-glucuronide.
Immunopharmacological profile of TEI-3096: a new immunomodulator.
TLDR
Results suggests that TEI-3096 restores the abnormal immune response and may be useful for the treatment of auto-immune disease such as rheumatoid arthritis.
Effect of TEI-3096 on experimental nephritis induced by calf serum in mice
TLDR
ま た,handlingの しやすい マウスを用いた報告は 少 な く,満 足 できるモ デルがないのが 現状 で あ る.
Effect of TEI-2117, a new antithrombotic agent: A fundamental study on platelet aggregation
TLDR
The result suggest that I may play in vivo effect on prevention of thrombus formation through antagonizing arachidonic acid metabolism in platelets.
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