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TBC 3214

Known as: TBC-3214, TBC3214 
National Institutes of Health

Related topics

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2 relations

Broader (2)

IsoxazolesSulfonamides

Papers overview

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2016
2016
Activation of Receptor Activator of Nuclear Factor-κB Ligand and Matrix Metalloproteinase Production in Periodontal Fibroblasts by Endothelin Signaling.
BACKGROUND Periodontitis is a group of inflammatory diseases affecting the tissues supporting the teeth that will progressively… 
2008
2008
The endothelin system mediates bone modeling in the late stage of orthodontic tooth movement in rats.
2007
2007
The effects of TBC3214, a selective endothelin ETA receptor antagonist, on orthodontic tooth movement in rats.
Many chemical messengers are involved in the process of alveolar bone and periodontal ligament remodelling during orthodontic… 
2006
2006
Effects of a specific endothelin-1A antagonist on exercise-induced pulmonary haemorrhage (EIPH) in thoroughbred horses.
REASONS FOR PERFORMING STUDY During high intensity exercise, the very high pulmonary artery pressure (Ppa) experienced by… 
2005
2005
Endothelin‐mediated remodeling in aortas of diabetic rats
Smooth muscle cells proliferation and extracellular matrix (ECM) protein deposition are key features of diabetic macroangiopathy… 
2001
2001
Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.
Sitaxsentan (3, TBC11251) (Wu et al. J. Med. Chem. 1997, 40, 1690) is an orally active ET(A) selective endothelin antagonist that… 
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