• Publications
  • Influence
  • C. Lamb, R. Dixon
  • Biology, Medicine
  • Annual review of plant physiology and plant…
  • 1 June 1997
Emerging data indicate that the oxidative burst reflects activation of a membrane-bound NADPH oxidase closely resembling that operating in activated neutrophils, which underlies the expression of disease-resistance mechanisms. Expand
Activation Tagging Identifies a Conserved MYB Regulator of Phenylpropanoid Biosynthesis
A novel approach for enhancing the accumulation of natural products based on activation tagging by Agrobacterium-mediated transformation with a T-DNA that carries cauliflower mosaic virus 35S enhancer sequences at its right border is reported. Expand
Stress-Induced Phenylpropanoid Metabolism.
Limiting discussion to stress-induced phenylpropanoids eliminates few of the structural classes, because many compounds that are constitutive in one plant species or tissue can be induced by various stresses in another species or in another tissue of the same plant. Expand
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
It is reported here that H2O2 from this oxidative burst not only drives the cross-linking of cell wall structural proteins, but also functions as a local trigger of programmed death in challenged cells and as a diffusible signal for the induction in adjacent cells of genes encoding cellular protectants. Expand
Activation tagging in Arabidopsis.
Activation tagging using T-DNA vectors that contain multimerized transcriptional enhancers from the cauliflower mosaic virus (CaMV) 35S gene has been applied to Arabidopsis plants, and it is shown that overexpressed genes are almost always found immediately adjacent to the inserted CaMV 35S enhancers. Expand
Nitric oxide functions as a signal in plant disease resistance
It is shown that nitric oxide potentiates the induction of hypersensitive cell death in soybean cells by reactive oxygen intermediates and functions independently of such intermediates to induce genes for the synthesis of protective natural products. Expand
Reactive Oxygen Intermediates Mediate a Systemic Signal Network in the Establishment of Plant Immunity
It is shown that inoculation of Arabidopsis leaves with avirulent Pseudomonas syringae induces secondary oxidative bursts in discrete cells in distant tissues, leading to low-frequency systemic micro-HRs. Expand
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis
The three-dimensional structure of CHS elucidates the chemical basis of plant polyketide biosynthesis and provides a framework for engineering CHS-like enzymes to produce new products. Expand
Lignin modification improves fermentable sugar yields for biofuel production
Recalcitrance to saccharification is a major limitation for conversion of lignocellulosic biomass to ethanol and lignin modification could bypass the need for acid pretreatment and thereby facilitate bioprocess consolidation. Expand
The Medicago Genome Provides Insight into the Evolution of Rhizobial Symbioses
The draft sequence of the M. truncatula genome sequence is described, a close relative of alfalfa (Medicago sativa), a widely cultivated crop with limited genomics tools and complex autotetraploid genetics, which provides significant opportunities to expand al falfa’s genomic toolbox. Expand