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TB 402

Known as: TB-402, TB402 monoclonal antibody 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Monoclonal Antibodies

Papers overview

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2013
2013
Single-dose TB-402 or rivaroxaban for the prevention of venous thromboembolism after total hip replacement. A randomised, controlled trial.
TB-402 is a long-acting monoclonal antibody that partially inhibits factor VIII. A single administration of TB-402 was effective… 
2012
2012
Partial versus complete factor VIII inhibition in a mouse model of venous thrombosis.
2012
2012
Antidote strategies to reverse anticoagulation with TB‐402, a long‐acting partial inhibitor of factor VIII
Summary.  Background:  TB‐402 is a partially inhibiting antibody of factor VIII that is under development as a long‐acting… 
2011
2011
Single intravenous administration of TB‐402 for the prophylaxis of venous thromboembolism after total knee replacement: a dose‐escalating, randomized, controlled trial
Summary.  Background: TB‐402 is a novel anticoagulant monoclonal antibody with a prolonged antithrombotic effect resulting from… 
Review
2011
Review
2011
New parenteral anticoagulants in development
The therapeutic armamentarium of parenteral anticoagulants available to clinicians is mainly composed by unfractionated heparin… 
2011
2011
Effects of a FVIII inhibitor TB-402 on coagulation: reversibility with pro-coagulants
2010
2010
Tolerability and pharmacokinetics of TB-402 in healthy male volunteers.
2010
2010
Single intravenous administration of TB-402 for the prophylaxis of VTE after total knee replacement surgery
Total VTE was lower in each of the TB-402 groups compared to the enoxaparin group: 16.7% (9.8-26.9), 23.9% (15.3-35.3), 24.1%(16… 
2009
2009
Thrombogram analysis of the long-acting anticoagulant effect of TB-402, a human anti-FVIII antibody, and of its interactions with rHVFIII, LMWH and Warfarin in healthy volunteers
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