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TAX1BP1 gene
Known as:
CALCOCO3
, HUMAN T-CELL LEUKEMIA VIRUS TYPE 1-BINDING PROTEIN
, TRAF6-INTERACTING PROTEIN
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National Institutes of Health
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Related topics
Related topics
1 relation
TIFA gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses
Qing Yang
,
Tian-Tian Liu
,
+7 authors
H. Shu
PLoS Pathogens
2017
Corpus ID: 42176893
Toll-like receptor (TLR)-mediated signaling are critical for host defense against pathogen invasion. However, excessive responses…
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Highly Cited
2016
Highly Cited
2016
Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
Andrew S. Moore
,
E. Holzbaur
Proceedings of the National Academy of Sciences…
2016
Corpus ID: 37364468
Significance Mitochondria are key regulators of cellular metabolism and are defective in a number of human disorders. Here, we…
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Highly Cited
2015
Highly Cited
2015
The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy
David A. Tumbarello
,
Paul T. Manna
,
+4 authors
F. Buss
PLoS Pathogens
2015
Corpus ID: 2504154
Autophagy plays a key role during Salmonella infection, by eliminating these pathogens following escape into the cytosol. In this…
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Highly Cited
2010
Highly Cited
2010
TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases*
K. Parvatiyar
,
G. Barber
,
E. Harhaj
Journal of Biological Chemistry
2010
Corpus ID: 38150372
Induction of type I interferons by the transcription factor IRF3 is essential in the initiation of antiviral innate immunity…
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Highly Cited
2009
Highly Cited
2009
The ubiquitin‐editing enzyme A20 requires RNF11 to downregulate NF‐κB signalling
Noula Shembade
,
K. Parvatiyar
,
Nicole S. Harhaj
,
E. Harhaj
EMBO Journal
2009
Corpus ID: 23410936
The RING domain protein RNF11 is overexpressed in breast cancers and promotes tumour growth factor‐beta (TGF‐β) signalling. RNF11…
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Highly Cited
2008
Highly Cited
2008
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
Noula Shembade
,
Nicole S. Harhaj
,
+4 authors
E. Harhaj
Nature Immunology
2008
Corpus ID: 205361147
The ubiquitin-editing enzyme A20 is a critical negative regulator of inflammation and cytokine-mediated activation of the…
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Highly Cited
2008
Highly Cited
2008
Inflammatory cardiac valvulitis in TAX1BP1‐deficient mice through selective NF‐κB activation
H. Iha
,
J. Péloponèse
,
+9 authors
K. Jeang
EMBO Journal
2008
Corpus ID: 574097
Nuclear factor kappa B (NF‐κB) is a key mediator of inflammation. Unchecked NF‐κB signalling can engender autoimmune pathologies…
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Highly Cited
2007
Highly Cited
2007
Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling.
Noula Shembade
,
Nicole S. Harhaj
,
D. Liebl
,
E. Harhaj
EMBO Journal
2007
Corpus ID: 34511484
The NF-kappaB transcription factor is normally transiently activated by proinflammatory cytokines and bacterial…
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Highly Cited
2004
Highly Cited
2004
Protein Profile of Tax-associated Complexes*
Kaili Wu
,
M. Bottazzi
,
+8 authors
F. Kashanchi
Journal of Biological Chemistry
2004
Corpus ID: 17335682
Infection with human T-cell leukemia virus type 1 (HTLV-1) results in adult T-cell leukemia and HTLV-1-associated myelopathy…
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Highly Cited
1999
Highly Cited
1999
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases
D. Valck
,
D. Jin
,
+5 authors
R. Beyaert
Oncogene
1999
Corpus ID: 25222137
A20 is a Cys2/Cys2 zinc finger protein which is induced by a variety of inflammatory stimuli and which has been characterized as…
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