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TAK-242

Known as: TAK 242, TAK242 
National Institutes of Health

Papers overview

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2020
2020
TAK-242, Toll-Like Receptor 4 Antagonist, Attenuates Brain Edema in Subarachnoid Hemorrhage Mice.
BACKGROUND Brain edema is a common and critical pathology following subarachnoid hemorrhage (SAH). Toll-like receptor 4 (TLR4… 
2020
2020
[Implications of EET in renal ischemia/reperfusion by regulating NLRP3 expression and pyroptosis].
Objective: To investigate the mechanism of epoxyeicosatrienoic acids (EET) on renal ischemia/reperfusion (I/R). Methods: Thirty… 
2019
2019
Effects of β2/aβ2 on oxLDL-induced CD36 activation in THP-1 macrophages.
2019
2019
Malignant fibrous histiocytoma amplified sequence 1 alleviates inflammation and renal fibrosis in diabetic nephropathy by inhibiting TLR4
Abstract Background: Diabetic nephropathy (DN) is the most common complication of diabetes mellitus (DM). The signal pathway and… 
2017
2017
Immunoregulatory Role of MicroRNA-21 in Macrophages in Response to Bacillus Calmette-Guerin Infection Involves Modulation of the TLR4/MyD88 Signaling Pathway
Background/Aims: The purpose of this study is to explore the immunoregulatory role of microRNA-21 (miR-21) targeting of the TLR4… 
2017
2017
A novel function of TLR4 in mediating the immunomodulatory effect of Benzanthrone, an environmental pollutant.
2017
2017
Extracellular HSP72 induces proinflammatory cytokines in human periodontal ligament fibroblast cells through the TLR4/NFκB pathway in vitro.
2016
2016
Uric acid induces TLR 4-dependent innate immune response but not HLA-DR and CD 40 activation in renal proximal tubular epithelial cells
Hyperuricemia correlates with the development and progression of renal diseases. We have previously revealed that uric acid (UA… 
Review
2014
Review
2014
What's new in the quagmire of sepsis?
2011
2011
TAKEDA-143242 increased survival via reduced cytokines in porcine peritonitis.
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