TAK-242

Known as: TAK 242, TAK242 
 
National Institutes of Health

Papers overview

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2015
2015
Toll-like receptor 4 (TLR4) contributes to cerebral ischemia/reperfusion (I/R) injury and is a potential target for the treatment… (More)
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2015
2015
BACKGROUND The current study investigated the analgesic effect of the Toll-like receptor 4 (TLR4) specific antagonist TAK-242 on… (More)
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Highly Cited
2014
Highly Cited
2014
Treatment of sickle cell disease (SCD) is hampered by incomplete understanding of pathways linking hemolysis to vaso-occlusion… (More)
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2013
2013
The innate immune response is the first line of defence against invading microorganisms and it is also activated in different… (More)
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Highly Cited
2011
Highly Cited
2011
TAK-242 (resatorvid), a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, inhibits the production of… (More)
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2011
2011
BACKGROUND This study was conducted to investigate the role of toll-like receptor 4 (TLR4) in mediating acute kidney injury in… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To evaluate whether TAK-242, a small-molecule inhibitor of Toll-like receptor-4-mediated signaling, suppresses cytokine… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND PURPOSE TAK-242, a novel synthetic small-molecule, suppresses production of multiple cytokines by inhibiting Toll… (More)
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Highly Cited
2008
Highly Cited
2008
TAK-242, a small-molecule antisepsis agent, has shown to suppress lipopolysaccharide (LPS)-induced inflammation. In this study… (More)
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Highly Cited
2006
Highly Cited
2006
Proinflammatory mediators such as cytokines and NO play pivotal roles in various inflammatory diseases. To combat inflammatory… (More)
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