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TAK 044

Known as: TAK-044 
 
National Institutes of Health

Papers overview

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2007
2007
BACKGROUND Endothelin-1 (ET-1) has been implicated in the pathophysiology of chronic kidney disease (CKD) and ET receptor… Expand
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2005
2005
Stroke causes brain injury in millions of people world wide each year. Despite the enormity of problem, currently there is no… Expand
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Highly Cited
2000
Highly Cited
2000
OBJECT Delayed cerebral ischemia remains an important cause of death and disability in patients who have suffered subarachnoid… Expand
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2000
2000
Object. Delayed cerebral ischemia remains an important cause of death and disability in patients who have suffered subarachnoid… Expand
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Highly Cited
2000
Highly Cited
2000
Patients with essential hypertension are characterized by impaired basal and agonist-evoked nitric oxide release and increased… Expand
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Highly Cited
1997
Highly Cited
1997
1. Endothelin-1 (ET-1) produces constriction of the rat mesenteric vascular bed in vivo via ETA and ETB receptor subtypes. The… Expand
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1996
1996
1. We examined the effects of systemic infusion, in healthy human volunteers, of the endothelin antagonist TAK-044 on the plasma… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Although local inhibition of the generation or actions of endothelin-1 has been shown to cause forearm vasodilatation… Expand
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1995
1995
1. The aims of the present study were to characterize the pharmacological profile of a new endothelin (ET) receptor antagonist… Expand
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1994
1994
Protective effects of a new endothelin (ET) receptor antagonist, TAK-044, were studied in a model of acute renal failure (ARF) in… Expand
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