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Hedgehog Signaling Pathway is a New Therapeutic Target for Patients with Breast Cancer
The Hedgehog (Hh) signaling pathway functions as an organizer in embryonic development. Genetic analysis has demonstrated a critical role for the Hh pathway in mammary gland morphogenesis. Disruption… Expand
An informative linkage map of soybean reveals QTLs for flowering time, leaflet morphology and regions of segregation distortion.
- N. Yamanaka, S. Ninomiya, +5 authors K. Harada
- Biology, Medicine
- DNA research : an international journal for rapid…
A genetic linkage map covering a large region of the genome with informative markers is essential for plant genome analysis, including identification of quantitative trait loci (QTLs), map-based… Expand
Purification, characterization and biological significance of tumor-derived exosomes.
- Kenichiro Koga, K. Matsumoto, +8 authors M. Katano
- Biology, Medicine
- Anticancer research
- 1 November 2005
Exosomes are nanovesicles that are released into the extracellular environment during the fusion of multivesicular bodies with the plasma membrane. Exosomes released from dendritic cells, dexosomes,… Expand
Dynamics of normal and injured human liver regeneration after hepatectomy as assessed on the basis of computed tomography and liver function
We compared liver volume and function kinetics after partial hepatectomy according to extent of resection and severity of coexisting liver disease in 57 adults with uneventful postoperative courses.… Expand
A Prediction Scoring System to Select the Surgical Treatment of Liver Cancer Further Refinement Based on 10 Years of Use
ObjectiveThis study reports further refinement of a prediction scoring system, which was established in 1980 as a guide to determine a safe limit for hepatectomy, based on 10 years of use. Summary… Expand
Nuclear factor-kappaB contributes to hedgehog signaling pathway activation through sonic hedgehog induction in pancreatic cancer.
The hedgehog (Hh) signaling pathway, which functions as an organizer in embryonic development, is implicated in the development of various tumors. In pancreatic cancer, pathway activation is reported… Expand
Bombyx orcokinins are brain‐gut peptides involved in the neuronal regulation of ecdysteroidogenesis
- N. Yamanaka, L. Roller, +4 authors Y. Tanaka
- Biology, Medicine
- The Journal of comparative neurology
- 1 February 2011
Biosynthesis of ecdysteroids, the insect steroid hormones controlling gene expression during molting and metamorphosis, takes place primarily in the prothoracic gland (PG). The activity of the PG is… Expand
Comparison of CT findings with resected specimens after chemoembolization with iodized oil for hepatocellular carcinoma.
- K. Takayasu, S. Arii, +7 authors M. Ohto
- AJR. American journal of roentgenology
- 1 September 2000
OBJECTIVE We assessed the role of dynamic CT in the evaluation of the efficacy of transarterial chemoembolization with iodized oil for hepatocellular carcinoma. MATERIALS AND METHODS We examined 41… Expand
Purification and Characterization of Aspartic Proteinase from Sunflower Seeds
- H. Park, N. Yamanaka, A. Mikkonen, I. Kusakabe, H. Kobayashi
- Medicine, Biology
- Bioscience, biotechnology, and biochemistry
- 1 January 2000
Aspartic proteinases were purified from sunflower seed extracts by affinity chromatography on a pepstatin A-EAH Sepharose column and by Mono Q column chromatography. The final preparation contained… Expand
Clinicopathologic spectrum of resected extraductal mass‐forming intrahepatic cholangiocarcinoma
Background. The mode of tumor growth of intrahepatic cholangiocarcinoma (CC) varies considerably from patient to patient. This study describes the clinicopathologic variety of the extraductal… Expand