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TAC1 gene

Known as: substance P, NEUROPEPTIDE K, NEUROMEDIN L 
This gene plays a role in the induction of behavioral responses and in vasodilation.
National Institutes of Health

Related topics

Related topics

11 relations
Intercellular Communication ProcessNeurokinin ANociceptionProtachykinin-1, human

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TAC1 wt Allele

Papers overview

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Highly Cited
2004
Highly Cited
2004
Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage
Sensory neuropeptides such as neurokinin A (NKA) or particularly substance P (SP) by neurokinin receptor (NK‐R) activation… 
Highly Cited
2001
Highly Cited
2001
Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum
Highly Cited
1998
Highly Cited
1998
Activation of spinal N-methyl-d-aspartate or neurokinin receptors induces long-term potentiation of spinal C-fibre-evoked potentials in spinalized rats
Highly Cited
1998
Highly Cited
1998
Characterization of neocortical non-pyramidal neurons expressing preprotachykinins A and B: a double immunofluorescence study in the rat
Highly Cited
1995
Highly Cited
1995
Neuropeptide gene expression and capsaicin‐sensitive primary afferents: maintenance and spread of adjuvant arthritis in the rat.
1. Many experimental and clinical arthritides are characterized by their bilateral nature. There is strong evidence to suggest… 
Highly Cited
1994
Highly Cited
1994
Altered tachykinin expression by dorsal root ganglion neurons in a rat model of neuropathic pain
Highly Cited
1993
Highly Cited
1993
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
The role of NK1 tachykinin receptors in the increase in total pulmonary resistance (RL) produced by release of endogenous… 
Highly Cited
1992
Highly Cited
1992
Localization of the tachykinin neurokinin B precursor peptide in rat brain by immunocytochemistry and in situ hybridization
Highly Cited
1990
Highly Cited
1990
gamma-Preprotachykinin-(72-92)-peptide amide: an endogenous preprotachykinin I gene-derived peptide that preferentially binds to neurokinin-2 receptors.
The presence of N-terminally extended forms of neurokinin A has recently been reported in the mammalian brain. Among them, gamma… 
Highly Cited
1986
Highly Cited
1986
Sequence analysis of cloned cDNA for rat substance P precursor: existence of a third substance P precursor.
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