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TA 3090

Known as: TA-3090 
National Institutes of Health

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clentiazem

Papers overview

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Review
1994
Review
1994
Antihypertensive therapy and progression of diabetic renal disease.
A number of changes in intrarenal hemodynamics and morphology are characteristic of diabetic nephropathy. These changes include… 
1994
1994
Effect of Clentiazem (TA‐3090) with Posttreatment on Neurologic and Histologic Disorders of Stroke‐Prone Spontaneously Hypertensive Rats with History of Stroke
Summary After stroke-prone spontaneously hypertensive rats (SHRSP) received a salt-loaded diet to accelerate onset of stroke, the… 
Highly Cited
1993
Highly Cited
1993
Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria.
The long-term effects of different antihypertensive regimens were studied in uninephrectomized beagles with alloxan-induced… 
1993
1993
Sustained Myocardial Protection by Clentiazem (TA‐3090) After a 90‐Minute Coronary Occlusion and 72 Hours of Reperfusion in Dogs with Collateral Flow
Summary: Reduction of infarct size by calcium channel blockers, given at reperfusion, has been reported with diltiazem and… 
1992
1992
Cerebral vasodilating and spasmolytic actions of a new Ca-antagonist, clentiazem (TA-3090), in anesthetized animals.
The effect of a new 1,5-benzothiazepine calcium antagonist, clentiazem (TA-3090), on the cerebral circulation was studied in… 
1991
1991
Effects of TA-3090, a new calcium channel blocker, on myocardial substrate utilization in ischemic and nonischemic isolated working fatty acid-perfused rat hearts.
Experimental studies have shown that calcium channel blockade has a protective effect on the ischemic myocardium. Although these… 
1991
1991
Binding characteristics of a new 1,5-benzothiazepine, clentiazem, to rat cerebral cortex and skeletal muscle membranes.
1991
1991
Vascular actions of TA 3090, a novel analog of diltiazem: interaction with endothelium-dependent relaxation in canine femoral and coronary arteries.
The effects of a new 1,5-benzothiazepine calcium antagonist, TA 3090 (an analog of diltiazem), were analyzed in isolated canine… 
1990
1990
[3H]TA-3090, a selective benzothiazepine-type calcium channel receptor antagonist: in vitro characterization.
Binding of the new benzothiazepine calcium channel blocker, (+)-(2S,3S)-3-acetoxy-8-chloro-5-(2-(dimethylamino)ethyl)-2,3-dihydro… 
1989
1989
Pharmacology of TA‐3090 (8‐Chloro Diltiazem) Related to Its Cerebrovascular Protective Properties
TA-3090 (8-chloro diltiazem) has been shown in three experimental circumstances to have cerebrovascular protective properties. In… 
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