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T-cell protein tyrosine phosphatase

Known as: T Cell Protein Tyrosine Phosphatase, Protein Tyrosine Phosphatase, Non Receptor Type 2, Protein Tyrosine Phosphatase, Non-Receptor Type 2 [Chemical/Ingredient] 
A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Many autoimmune diseases exhibit familial aggregation, indicating that they have genetic determinants. Single nucleotide… Expand
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Highly Cited
2005
Highly Cited
2005
The proinflammatory cytokine tumor necrosis factor (TNF) modulates cellular responses through the mitogen-activated protein… Expand
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Highly Cited
2004
Highly Cited
2004
The deregulation of the immune response is a critical component in inflammatory disease. Recent in vitro data show that T-cell… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT The platelet-derived growth factor (PDGF) β receptor mediates mitogenic and chemotactic signals. Like other tyrosine… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Upon interferon (IFN) stimulation, Stat1 becomes tyrosine phosphorylated and translocates into the nucleus, where it… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The immune response is regulated through a tightly controlled cytokine network. The counteracting balance between… Expand
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Highly Cited
2002
Highly Cited
2002
Protein-tyrosine phosphatase 1B (PTP1B) has recently received much attention as a potential drug target in type 2 diabetes. This… Expand
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Highly Cited
2002
Highly Cited
2002
In the previous study, we demonstrated that the nuclear isoform of T-cell protein-tyrosine phosphatase (TC-PTP) dephosphorylated… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT T-cell protein tyrosine phosphatase (TCPTP) exists as two forms generated by alternative splicing: a 48-kDa endoplasmic… Expand
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Highly Cited
1997
Highly Cited
1997
The T cell protein tyrosine phosphatase (TC-PTP) is one of the most abundant mammalian tyrosine phosphatases in hematopoietic… Expand
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