PTPN2 gene

Known as: protein tyrosine phosphatase, non-receptor type 2, TC-PTP, PROTEIN-TYROSINE PHOSPHATASE, T-CELL 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Immunotherapy with PD-1 checkpoint blockade is effective in only a minority of patients with cancer, suggesting that additional… (More)
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Highly Cited
2011
Highly Cited
2011
Crohn's disease (CD) and celiac disease (CelD) are chronic intestinal inflammatory diseases, involving genetic and environmental… (More)
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2011
2011
We have recently reported inactivation of the tyrosine phosphatase PTPN2 (also known as TC-PTP) through deletion of the entire… (More)
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2011
2011
The IL-2/IL-2R signaling pathway has an important role in autoimmunity. Several genes identified in genome-wide association (GWA… (More)
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Highly Cited
2010
Highly Cited
2010
Initially thought to play a restricted role in calcium homeostasis, the pleiotropic actions of vitamin D in biology and their… (More)
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2010
2010
PTPN2 (protein tyrosine phosphatase non-receptor type 2, also known as TC-PTP) is a cytosolic tyrosine phosphatase that functions… (More)
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2010
2010
The Wellcome Trust Case Control Consortium (WTCCC) genome-wide study found association of PTPN2 with three autoimmune diseases… (More)
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Highly Cited
2009
Highly Cited
2009
With more than 12 million people affected worldwide, 2 million new cases occurring per year, and the rapid emergence of drug… (More)
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2009
2009
OBJECTIVE The pathogenesis of type 1 diabetes has a strong genetic component. Genome-wide association scans recently identified… (More)
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Highly Cited
1997
Highly Cited
1997
Thymidine dinucleotide (pTpT) stimulates melanogenesis in mammalian pigment cells and intact skin, mimicking the effects of UV… (More)
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