T-Cell Surface Glycoprotein, human
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CD1a is a lipid-presenting molecule that is abundantly expressed on Langerhans cells. However, the in vivo role of CD1a has… Expand A central paradigm in αβ T cell–mediated immunity is the simultaneous co-recognition of antigens and antigen-presenting molecules… Expand The antigen-presenting molecules CD1 and MHC class I-related protein (MR1) display lipids and small molecules to T cells. The… Expand T cells autoreactive to the antigen-presenting molecule CD1a are common in human blood and skin, but the search for natural… Expand CD1 activates T cells, but the function and size of the possible human T cell repertoires that recognize each of the CD1 antigen… Expand CD1 proteins are a family of major histocompatibility complex (MHC) class I‐like antigen‐presenting molecules that present lipids… Expand Langerhans cells (LCs) constitute a subset of DCs that initiate immune responses in skin. Using leprosy as a model, we… Expand CD1 antigens bind a variety of self and foreign lipid and glycolipid antigens for presentation to CD1-restricted T cell receptors… Expand Low CD1a-positive putative dendritic cell numbers in human breast cancer has recently been described and may explain the apparent… Expand The immunoreactivity of a CD1a monoclonal antibody (MAb), denoted 010, was investigated by means of the streptavidin‐biotin… Expand