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T-Cell Surface Glycoprotein, human

Known as: Cortical Thymocyte Antigen CD1A, T-Cell Surface Antigen T6/Leu-6, Antigen CD1a 
T-cell surface glycoprotein CD1a (327 aa, ~37 kDa) is encoded by the human CD1A gene. This protein is involved in the mediation of lipid and… Expand
National Institutes of Health

Papers overview

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2016
2016
The discovery of PIWI-interacting RNAs (piRNAs) revealed the complexity of the RNA world. Although piRNAs were first deemed to be… Expand
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Highly Cited
2015
Highly Cited
2015
A central paradigm in αβ T cell–mediated immunity is the simultaneous co-recognition of antigens and antigen-presenting molecules… Expand
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Highly Cited
2014
Highly Cited
2014
T cells autoreactive to the antigen-presenting molecule CD1a are common in human blood and skin, but the search for natural… Expand
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2013
2013
Human CD1a mediates foreign Ag recognition by a T cell clone, but the nature of possible TCR interactions with CD1a/lipid are… Expand
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Highly Cited
2010
Highly Cited
2010
CD1 activates T cells, but the function and size of the possible human T cell repertoires that recognize each of the CD1 antigen… Expand
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2008
2008
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids… Expand
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2006
2006
Self-glycosphingolipids bind to surface CD1 molecules and are readily displaced by other CD1 ligands. This capacity to exchange… Expand
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Highly Cited
2004
Highly Cited
2004
Langerhans cells (LCs) constitute a subset of DCs that initiate immune responses in skin. Using leprosy as a model, we… Expand
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Highly Cited
2003
Highly Cited
2003
CD1 antigens bind a variety of self and foreign lipid and glycolipid antigens for presentation to CD1-restricted T cell receptors… Expand
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2002
2002
Low CD1a-positive putative dendritic cell numbers in human breast cancer has recently been described and may explain the apparent… Expand
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