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T-Cell Receptors alpha-Chain
Known as:
T-Cell Receptor Alpha Chain
, TRA
, T Cell Receptors alpha Chain
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One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active gene.
National Institutes of Health
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Related topics
Related topics
3 relations
T-Cell Activation
TRA gene
alpha-beta T-Cell Receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Regulation of T cell receptor-alpha gene recombination by transcription.
Iratxe Abarrategui
,
M. Krangel
Nature Immunology
2006
Corpus ID: 37632736
Despite the longstanding correlation between transcription and variable-(diversity)-joining (V(D)J) recombination, it is unknown…
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2004
2004
Sequence analysis of the human αβ T-cell receptor CDR3 region
P. Moss
,
J. Bell
Immunogenetics
2004
Corpus ID: 24587613
Although the three-dimensional structure of the T-cell receptor (TCR) has not yet been determined, several groups have proposed…
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2003
2003
Surprisingly minor influence of TRAV11 (Vα14) polymorphism on NK T-receptor mCD1/α-galactosylceramide binding kinetics
B. Sim
,
K. Holmberg
,
+5 authors
N. Gascoigne
Immunogenetics
2003
Corpus ID: 44498957
Abstract.Defects in natural killer T (NK T) cell function and of interleukin-4 -production in SJL and NOD mice have been linked…
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2001
2001
Cysticercus Antigens in Cerebrospinal Fluid Samples from Patients with Neurocysticercosis
A. Pardini
,
A. Vaz
,
L. R. Machado
,
J. Livramento
Journal of Clinical Microbiology
2001
Corpus ID: 18134674
ABSTRACT Antigens were detected in cerebrospinal fluid (CSF) samples from patients with neurocysticercosis (NC) by enzyme-linked…
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2000
2000
Performance of the ELISA test for swine cysticercosis using antigens of Taenia solium and Taenia crassiceps cysticerci.
P.S.A. Pinto
,
Adelaide José Vaz
,
Pedro Manuel Leal Germano
,
P. M. Nakamura
Veterinary parasitology
2000
Corpus ID: 22726185
Review
1999
Review
1999
Invariant or highly conserved TCR alpha are expressed on double-negative (CD3+CD4-CD8-) and CD8+ T cells.
M. Han
,
L. Harrison
,
P. Kehn
,
K. Stevenson
,
J. Currier
,
M. Robinson
Journal of Immunology
1999
Corpus ID: 23913493
TCR alpha (TCRA) expression was examined in RNA samples from PBMC and isolated populations of CD4+, CD8+, and DN T cells from 15…
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1998
1998
Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage
S. Page
,
L. Bogatzki
,
+5 authors
A. Pullen
1998
Corpus ID: 44011299
Abstract The majority of T cells develop in the thymus and exhibit well characterized phenotypic changes associated with their…
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1990
1990
An interspecific backcross linkage map of the proximal half of mouse chromosome 14.
J. Ceci
,
D. Kingsley
,
C. Silan
,
N. Copeland
,
N. Jenkins
Genomics
1990
Corpus ID: 30625863
1986
1986
Recombinant interferon alpha can induce rearrangement of T-cell antigen receptor alpha-chain genes and maturation to cytotoxicity in T-lymphocyte clones in vitro.
L. Chen
,
D. Mathieu-Mahul
,
F. Bach
,
J. Dausset
,
A. Bensussan
,
M. Sasportes
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 40825345
T-cell receptor genes are found in the germ-line configuration as well as in rearranged forms, as detected in T lymphocytes by…
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1986
1986
Assignment of pancreatic ribonuclease gene to mouse chromosome 14.
R. Elliott
,
L. Samuelson
,
M. Lambert
,
M. Meisler
Cytogenetics and Cell Genetics
1986
Corpus ID: 46759462
A pancreatic ribonuclease cDNA was used as a probe for Southern blot hybridization of genomic DNA from recombinant inbred strains…
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