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T-Cell Receptors alpha-Chain

Known as: T-Cell Receptor Alpha Chain, TRA, T Cell Receptors alpha Chain 
One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active gene.
National Institutes of Health

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3 relations
T-Cell ActivationTRA genealpha-beta T-Cell Receptor

Papers overview

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Highly Cited
2006
Highly Cited
2006
Regulation of T cell receptor-alpha gene recombination by transcription.
Despite the longstanding correlation between transcription and variable-(diversity)-joining (V(D)J) recombination, it is unknown… 
2004
2004
Sequence analysis of the human αβ T-cell receptor CDR3 region
Although the three-dimensional structure of the T-cell receptor (TCR) has not yet been determined, several groups have proposed… 
2003
2003
Surprisingly minor influence of TRAV11 (Vα14) polymorphism on NK T-receptor mCD1/α-galactosylceramide binding kinetics
Abstract.Defects in natural killer T (NK T) cell function and of interleukin-4 -production in SJL and NOD mice have been linked… 
2001
2001
Cysticercus Antigens in Cerebrospinal Fluid Samples from Patients with Neurocysticercosis
ABSTRACT Antigens were detected in cerebrospinal fluid (CSF) samples from patients with neurocysticercosis (NC) by enzyme-linked… 
2000
2000
Performance of the ELISA test for swine cysticercosis using antigens of Taenia solium and Taenia crassiceps cysticerci.
Review
1999
Review
1999
Invariant or highly conserved TCR alpha are expressed on double-negative (CD3+CD4-CD8-) and CD8+ T cells.
TCR alpha (TCRA) expression was examined in RNA samples from PBMC and isolated populations of CD4+, CD8+, and DN T cells from 15… 
1998
1998
Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage
Abstract The majority of T cells develop in the thymus and exhibit well characterized phenotypic changes associated with their… 
1990
1990
An interspecific backcross linkage map of the proximal half of mouse chromosome 14.
1986
1986
Recombinant interferon alpha can induce rearrangement of T-cell antigen receptor alpha-chain genes and maturation to cytotoxicity in T-lymphocyte clones in vitro.
T-cell receptor genes are found in the germ-line configuration as well as in rearranged forms, as detected in T lymphocytes by… 
1986
1986
Assignment of pancreatic ribonuclease gene to mouse chromosome 14.
A pancreatic ribonuclease cDNA was used as a probe for Southern blot hybridization of genomic DNA from recombinant inbred strains… 
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