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T-Cell Development

Known as: T-Cell Differentiation, T-Lymphocyte Development, T-Cell Ontogeny 
Development of bone marrow-derived stem cells in the thymus through stages of positive selection under the influence of epithelial cells in the… 
National Institutes of Health

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41 relations
ATM geneATM protein, humanATM wt AlleleCD46 gene

Papers overview

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Review
2000
Review
2000
Molecular aspects of T-cell differentiation.
Differentiated T helper 1 (Th1) and T helper 2 (Th2) T-cells show striking differences in their patterns of cytokine expression… 
Highly Cited
1998
Highly Cited
1998
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation.
The functional receptor for the inflammatory cytokine IL-6 is composed of the ligand binding IL-6 receptor alpha chain (IL-6R… 
Highly Cited
1996
Highly Cited
1996
Interleukin-7 is a critical growth factor in early human T-cell development.
Highly purified human CD34+ fetal liver stem cells differentiate to mature T cells when seeded in vitro into isolated fetal… 
Highly Cited
1990
Highly Cited
1990
Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus…
Individuals infected by the human immunodeficiency virus type 1 (HIV-1) demonstrate progressive depletion and qualitative… 
Highly Cited
1987
Highly Cited
1987
Thy-1+ dendritic epidermal cells belong to the T-cell lineage.
The murine epidermis contains a population of dendritic, Thy-1+ cells (Thy-1+ DEC). Although it is now clear that these cells are… 
Highly Cited
1985
Highly Cited
1985
Rearrangement of T-cell receptor beta-chain genes during T-cell development.
The kinetics and order of rearrangements in the gene complex encoding T-cell-receptor beta chains were studied by Southern blot… 
Highly Cited
1985
Highly Cited
1985
Expression of genes of the T-cell antigen receptor complex in precursor thymocytes
The antigen receptor on Tlymphocytes has recently been characterized as a heterodimeric, transmembrane glycoprotein consisting of… 
Highly Cited
1983
Highly Cited
1983
Stable transformation of mouse L cells for human membrane T-cell differentiation antigens, HLA and beta 2-microglobulin: selection by fluorescence-activated cell sorting.
We isolated stable transformants of mouse L cells expressing human cell surface differentiation antigens by using… 
Highly Cited
1983
Highly Cited
1983
Monoclonal antibody characterization of surface antigens in childhood T-cell lymphoid malignancies.
Although childhood T-cell acute lymphocytic leukemia (T-ALL) and T-cell non-Hodgkin's lymphoma (T-NHL) have certain clinical… 
Highly Cited
1980
Highly Cited
1980
T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to the antigens Lyt-1, Lyt-2, and ThB1.
The phenotypes of thymus cells for the antigens Lyt-1, Lyt-2 and ThB have been analyzed by using immunofluorescence techniques… 
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