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T 98475

Known as: T-98475 
 
National Institutes of Health

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2 relations

Broader (2)

PyridonesThiophenes

Papers overview

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2006
2006
Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor…
Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one-based non-peptide luteinizing hormone… Expand
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2003
2003
Discovery of a thieno[2,3-d]pyrimidine-2,4-dione bearing a p-methoxyureidophenyl moiety at the 6-position: a highly potent and orally bioavailable non-peptide antagonist for the human luteinizing…
We have previously disclosed the first potent and orally effective non-peptide antagonist for the human luteinizing hormone… Expand
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2000
2000
Consensus bioactive conformation of cyclic GnRH antagonists defined by NMR and molecular modeling.
Little is known of the conformation of peptide hormones as they interact with their receptors for a number of reasons: peptide… Expand
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