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T 98

Known as: T-98 
National Institutes of Health

Papers overview

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2018
2018
Comparison of a ceramidase inhibitor (ceranib-2) with C2 ceramide and cisplatin on cytotoxicity and apoptosis of glioma cells.
Inhibiting ceramidase activity in cancer cells has been identified as a promising target for cancer therapy in recent studies… 
2014
2014
Modulation of uPA, MMPs and their inhibitors by a novel nutrient mixture in human glioblastoma cell lines.
Brain tumors are highly aggressive tumors that are characterized by high levels of matrix metalloproteinase (MMP)-2 and -9… 
2011
2011
Three novel members of angucycline group from Streptomyces sp. N05WA963
Three novel members of angucycline family named N05WA963A (1), B (2) and D (4), together with a new anthracycline named N05WA963C… 
2005
2005
Effect of a cytotoxic analog of LH-RH (T-98) on the growth of estrogendependent MXT mouse mammary cancers: Correlations between growth characteristics and EGF receptor content of tumors
SummaryFemale BDF mice bearing estrogen-dependent MXT mouse mammary cancers were treated for 4 weeks with a cytotoxic analog of… 
2005
2005
Effect of treatment with LHRH analogs containing cytotoxic radicals on the binding characteristics of receptors for luteinizing-hormone-releasing hormone in MXT mouse mammary carcinoma
Binding capacities and apparent dissociation constants of receptors for luteinizing-hormone-releasing hormone (LHRH) were… 
1994
1994
LH-RH analogue carrying a cytotoxic radical is internalized by rat pituitary cells in vitro
1993
1993
Inhibition of growth of experimental prostate cancer in rats by LH‐RH analogs linked to cytotoxic radicals
The effects of hybrid cytotoxic LH‐RH analogs, produced by linking anthraquinone or methotrexate to carrier LH‐RH agonist [D‐Lys6… 
1992
1992
Effect of luteinizing hormone‐releasing hormone analogs containing cytotoxic radicals on growth of estrogen‐independent MXT mouse mammary carcinoma in vivo
Cytotoxic luteinizing hormone-releasing hormone (LH-RH) analogs, AJ-004 (agonist [D-Lys6]LH-RH linked to methotrexate (MTX)), T… 
1989
1989
Plant antimutagenic agents, 7. Structure and antimutagenic properties of cymobarbatol and 4-isocymobarbatol, new cymopols from green alga (Cymopolia barbata).
Two new compounds, cymobarbatol and 4-isocymobarbatol, were isolated from the marine alga Cymopolia barbata. The complete… 
1988
1988
Plant antimutagenic agents, 4. Isolation and structure elucidation of maesol, an inactive constituent of Maesa spp.
Maesol, a novel dimeric phenol, was isolated from seeds of Maesa montana and Maesa indica. Maesol was shown to have the formula… 
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