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T 686

Known as: T-686 
National Institutes of Health

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2 relations

Broader (2)

Benzylidene CompoundsSuccinimides

Papers overview

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2010
2010
Synthesis and evaluation of 1,4-diphenylbutadiene derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) production.
1997
1997
Protective effect of T-686, an inhibitor of plasminogen activator inhibitor-1 production, against the lethal effect of lipopolysaccharide in mice.
We have examined the effects of an inhibitor of plasminogen activator inhibitor-1 (PAI-1) production, (3E,4E)-3-benzylidene-4-(3… 
1997
1997
A new butadiene derivative, T-686, inhibits plasminogen activator inhibitor type-1 production in vitro by cultured human vascular endothelial cells and development of atherosclerotic lesions in vivo…
1997
1997
T-686, a novel inhibitor of plasminogen activator inhibitor-1, inhibits thrombosis without impairment of hemostasis in rats.
1997
1997
A novel inhibitor of plasminogen activator inhibitor-1 production, T-686: direct effects on the fibrinolytic system
1997
1997
A NEW BUTADIENEDERIVATIVE,T-686, INHIBITSPLASMINOGEN ACTIVATORINHIBITORTYPE-1 PRODUCTION IN VITROBY CULTURED HUMANVASCULARENDOTHELL4LCELLS ANDDEVELOPMENTOF ATHEROSCLEROTIC LESIONSINVIVOIN RABBITS
Plasminogenactivatorinhibitor-1(PAI-1),the major physiologicinhibitorof tissue- type plasminogenactivatorand urokinase,is… 
1996
1996
Inhibitory effect of a new butadiene derivative on the production of plasminogen activator inhibitor-1 in cultured bovine endothelial cells.
Tissue-type plasminogen activator (t-PA) and its physiological inhibitor, plasminogen activator inhibitor-1 (PAI-1), are known to… 
1996
1996
A novel inhibitor of plasminogen activator inhibitor-1, T-686, modulates development of atherosclerosis in vivo in rabbits
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