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Succinimides
Known as:
succinimide
, Butanimides
, Pyrrolidinediones
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A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet…
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National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (45)
3,3,4,4-tetramethylsuccinimide
3-benzyl-N-(methanesulfonyloxy)succinimide
3-maleimidobenzoyl N-hydroxysuccinimide
5-(6)-carboxyfluorescein diacetate succinimidyl ester
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In Blood
Succinates
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
B. Shen
,
Keyang Xu
,
+30 authors
J. R. Junutula
Nature Biotechnology
2012
Corpus ID: 205276540
The reactive thiol in cysteine is used for coupling maleimide linkers in the generation of antibody conjugates. To assess the…
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Highly Cited
2003
Highly Cited
2003
Femtomolar detection of prostate-specific antigen: an immunoassay based on surface-enhanced Raman scattering and immunogold labels.
Desiree S. Grubisha
,
R. Lipert
,
Hye-Young Park
,
J. Driskell
,
M. Porter
Analytical chemistry
2003
Corpus ID: 22863792
A novel reagent for low-level detection in immunoadsorbent assays is described. The reagent consists of gold nanoparticles…
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Highly Cited
2001
Highly Cited
2001
Identification of multiple sources of charge heterogeneity in a recombinant antibody.
R. Harris
,
B. Kabakoff
,
+7 authors
A. Chen
Journal of chromatography. B, Biomedical sciences…
2001
Corpus ID: 36025824
Highly Cited
2001
Highly Cited
2001
Block of cloned human T-type calcium channels by succinimide antiepileptic drugs.
J. Gomora
,
A. Daud
,
M. Weiergräber
,
E. Perez-Reyes
Molecular pharmacology
2001
Corpus ID: 7098669
Inhibition of T-type Ca(2+) channels has been proposed to play a role in the therapeutic action of succinimide antiepileptic…
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Highly Cited
2000
Highly Cited
2000
Isoaspartate in peptides and proteins: formation, significance, and analysis.
D. Aswad
,
M. Paranandi
,
B. T. Schurter
Journal of pharmaceutical and biomedical analysis
2000
Corpus ID: 5751070
Highly Cited
1997
Highly Cited
1997
Capacitive monitoring of protein immobilization and antigen-antibody reactions on monomolecular alkylthiol films on gold electrodes.
V. Mirsky
,
M. Riepl
,
O. Wolfbeis
Biosensors & bioelectronics
1997
Corpus ID: 30429313
Highly Cited
1989
Highly Cited
1989
Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins.
R. Stephenson
,
S. Clarke
The Journal of biological chemistry
1989
Corpus ID: 3135263
Highly Cited
1987
Highly Cited
1987
Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
T. Geiger
,
S. Clarke
The Journal of biological chemistry
1987
Corpus ID: 35710204
Highly Cited
1987
Highly Cited
1987
Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins.
S. Clarke
International journal of peptide and protein…
1987
Corpus ID: 21155185
One mechanism for the spontaneous degradation of polypeptides is the intramolecular attack of the peptide bond nitrogen on the…
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Highly Cited
1983
Highly Cited
1983
Radioimmunoassay of cholecystokinin in human tissue and plasma.
J. Jansen
,
C. Lamers
Clinica chimica acta; international journal of…
1983
Corpus ID: 34091535
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