Skip to search formSkip to main contentSkip to account menu

Succinimides

Known as: succinimide, Butanimides, Pyrrolidinediones 
A subclass of IMIDES with the general structure of pyrrolidinedione. They are prepared by the distillation of ammonium succinate. They are sweet… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (45)

3,3,4,4-tetramethylsuccinimide3-benzyl-N-(methanesulfonyloxy)succinimide3-maleimidobenzoyl N-hydroxysuccinimide5-(6)-carboxyfluorescein diacetate succinimidyl ester
Expand
In BloodSuccinatesagonistsantagonists & inhibitors
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
The reactive thiol in cysteine is used for coupling maleimide linkers in the generation of antibody conjugates. To assess the… 
Highly Cited
2003
Highly Cited
2003
Femtomolar detection of prostate-specific antigen: an immunoassay based on surface-enhanced Raman scattering and immunogold labels.
A novel reagent for low-level detection in immunoadsorbent assays is described. The reagent consists of gold nanoparticles… 
Highly Cited
2001
Highly Cited
2001
Identification of multiple sources of charge heterogeneity in a recombinant antibody.
Highly Cited
2001
Highly Cited
2001
Block of cloned human T-type calcium channels by succinimide antiepileptic drugs.
Inhibition of T-type Ca(2+) channels has been proposed to play a role in the therapeutic action of succinimide antiepileptic… 
Highly Cited
2000
Highly Cited
2000
Isoaspartate in peptides and proteins: formation, significance, and analysis.
Highly Cited
1997
Highly Cited
1997
Capacitive monitoring of protein immobilization and antigen-antibody reactions on monomolecular alkylthiol films on gold electrodes.
Highly Cited
1989
Highly Cited
1989
Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins.
Highly Cited
1987
Highly Cited
1987
Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
Highly Cited
1987
Highly Cited
1987
Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins.
  • S. Clarke
  • International journal of peptide and protein…
  • 1987
  • Corpus ID: 21155185
One mechanism for the spontaneous degradation of polypeptides is the intramolecular attack of the peptide bond nitrogen on the… 
Highly Cited
1983
Highly Cited
1983
Radioimmunoassay of cholecystokinin in human tissue and plasma.
  • J. Jansen, C. Lamers
  • Clinica chimica acta; international journal of…
  • 1983
  • Corpus ID: 34091535
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License