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T 1106

Known as: T-1106, T1106 cpd 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

NucleosidesPyrazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
AZT acts as an anti-influenza nucleotide triphosphate targeting the catalytic site of A/PR/8/34/H1N1 RNA dependent RNA polymerase
  • N. S. Pagadala
  • Journal of Computer-Aided Molecular Design
  • 2019
    • Corpus ID: 73426896
To develop potent drugs that inhibit the activity of influenza virus RNA dependent RNA polymerase (RdRp), a set of compounds… Expand
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2018
2018
Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis
Dengue virus affects millions of people worldwide each year. To date, there is no drug for the treatment of dengue-associated… Expand
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2017
2017
Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers
Summary RNA viruses pose a threat to public health that is exacerbated by the dearth of antiviral therapeutics. The RNA… Expand
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2017
2017
Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus.
Antiviral agents are increasingly considered an option for veterinary medicine. An understanding of their mechanism of activity… Expand
2017
2017
Mutagen resistance and mutation restriction of St. Louis encephalitis virus.
The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral… Expand
2016
2016
Mutagen resistance and mutation restriction of St. Louis encephalitis virus.
The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral… Expand
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Highly Cited
2010
Highly Cited
2010
Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models.
Several studies have reported favipiravir (T-705) to be effective in treating a number of viral diseases modeled in rodent… Expand
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Review
2009
Review
2009
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections
Abstract A series of pyrazinecarboxamide derivatives T-705 (favipiravir), T-1105 and T-1106 were discovered to be candidate… Expand
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Highly Cited
2008
Highly Cited
2008
Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106
ABSTRACT Treatment with the nucleoside analog T-1106 was previously shown to be effective in a hamster model of yellow fever… Expand
2007
2007
Activity of T-1106 in a Hamster Model of Yellow Fever Virus Infection
ABSTRACT Yellow fever virus (YFV) causes 30,000 deaths worldwide, despite the availability of a vaccine. There are no approved… Expand
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