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T 0070907

Known as: T-0070907, T0070907 
National Institutes of Health

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2 relations

Broader (2)

BenzamidesPyridines

Papers overview

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2011
2011
The PPARgamma antagonist T0070907 suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.
BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARγ) is overexpressed in many types of cancer, including breast… 
2011
2011
Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression.
Highly Cited
2008
Highly Cited
2008
Antitumorigenic Effects of Peroxisome Proliferator-Activated Receptor-γ in Non-Small-Cell Lung Cancer Cells Are Mediated by Suppression of Cyclooxygenase-2 via Inhibition of Nuclear Factor-κB
Pharmacological activators of peroxisome proliferator-activated receptor-γ (PPARγ) inhibit growth of non-small-cell lung cancer… 
2008
2008
Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
Although peroxisome proliferator-activated receptor gamma (PPARgamma) is strongly expressed in the intestinal epithelium, the… 
2007
2007
Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner.
Peroxisome proliferator activated receptor (PPAR) gamma is a nuclear receptor involved primarily in lipid and glucose metabolism… 
Highly Cited
2006
Highly Cited
2006
Altered PPARgamma expression and activation after transient focal ischemia in rats.
Stroke is a devastating disease with limited treatment options. Recently, we found that the peroxisome proliferator-activated… 
2006
2006
PPARγ antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-Deoxy-Δ12,14-Prostaglandin J2
2006
2006
Peroxisome proliferator-activated receptor-γ antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia*
Objective:There is evidence that a) ligands of the nuclear receptor peroxisome proliferator-activated receptor (PPAR)-γ and b… 
Highly Cited
2005
Highly Cited
2005
PPARγ antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis
2004
2004
Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism.
Capsaicin, a major ingredient of hot pepper, is considered to exhibit anti-inflammatory properties. Our previous study… 
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