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Systemic Inflammatory Response Syndrome

Known as: Sepsis Syndromes, septic syndrome, Syndrome, Sepsis 
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees… 
National Institutes of Health

Related topics

Related topics

12 relations
In BloodMicrobiologicalPerinatal TerminologyRespiratory Distress Syndrome, Adult

Broader (1)

Sepsis

Papers overview

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Highly Cited
2006
Highly Cited
2006
The effect of hydroxyethyl starch and other plasma volume substitutes on endothelial cell activation; an in vitro study
ObjectiveTo study the effect of medium molecular weight hydroxyethyl starches on endothelial cell and neutrophil activation in… 
Highly Cited
2005
Highly Cited
2005
Intraoperative splanchnic hypoperfusion, increased intestinal permeability, down-regulation of monocyte class II major histocompatibility complex expression, exaggerated acute phase response, and…
Review
2000
Review
2000
ANTICYTOKINE THERAPIES FOR ACUTE INFLAMMATION AND THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME: IL‐10 AND ISCHEMIA/REPERFUSION INJURY AS A NEW PARADIGM
ABSTRACT The results of recent anticytokine trials for sepsis syndrome have been disappointing. Several Phase II and Phase III… 
Review
1999
Review
1999
Biologic Activities of the Contact Factors In Vivo
Three plasma proteins, namely, Factor XII (Hageman factor), prekallikrein (Fletcher factor), and high molecular weight kininogen… 
Highly Cited
1998
Highly Cited
1998
Pulmonary and Hepatic Gene Expression following Cecal Ligation and Puncture: Monophosphoryl Lipid A Prophylaxis Attenuates Sepsis-Induced Cytokine and Chemokine Expression and Neutrophil Infiltration
ABSTRACT Polymicrobial sepsis induced by cecal ligation and puncture (CLP) reproduces many of the pathophysiologic features of… 
Review
1996
Review
1996
Is it time to reposition vasopressors and inotropes in sepsis?
OBJECTIVES To review the literature on the current use of vasopressors and inotropes in patients with sepsis and sepsis syndrome… 
1995
1995
The Systemic Inflammatory Response Syndrome (SIRS)
Sepsis and multiple organ failure remain as important causes of mortality and morbidity in hospitals around the world today… 
Highly Cited
1995
Highly Cited
1995
Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo.
The receptor for urokinase plasminogen activator (uPA-R, CD87) is a glycosylphosphatidylinositol (GPI)-anchored 50 to 65 kD… 
Highly Cited
1976
Highly Cited
1976
Site of action of a soluble immune response suppressor (SIRS) produced by concanavalin A-activated spleen cells.
The cellular site of action of SIRS, a soluble immune response suppressor released by Con A-activated spleen cells which… 
Highly Cited
1976
Highly Cited
1976
Biological expressions of lymphocyte activation. V. Characterization of a soluble immune response suppressor (SIRS) produced by concanavalin A-activated spleen cells.
Supernatant fluids from murine spleen cell cultures incubated with concanavalin A for 48 hr contain a factor(s), soluble immune… 
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