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Systemic Inflammatory Response Syndrome

Known as: Sepsis Syndromes, septic syndrome, Syndrome, Sepsis 
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees… Expand
National Institutes of Health

Related topics

Related topics

12 relations
In BloodMicrobiologicalPerinatal TerminologyRespiratory Distress Syndrome, Adult
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Broader (1)

Sepsis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
IMPORTANCE Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the… Expand
Highly Cited
2015
Highly Cited
2015
Systemic inflammatory response syndrome criteria in defining severe sepsis.
BACKGROUND The consensus definition of severe sepsis requires suspected or proven infection, organ failure, and signs that meet… Expand
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Highly Cited
2010
Highly Cited
2010
Circulating Mitochondrial DAMPs Cause Inflammatory Responses to Injury
Injury causes a systemic inflammatory response syndrome (SIRS) that is clinically much like sepsis. Microbial pathogen-associated… Expand
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Review
2006
Review
2006
The systemic inflammatory response syndrome.
The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the… Expand
Review
2004
Review
2004
Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome
Inflammatory response leading to organ dysfunction and failure continues to be the major problem after injury in many clinical… Expand
Highly Cited
2000
Highly Cited
2000
The systemic inflammatory response syndrome in acute liver failure
The systemic inflammatory response syndrome (SIRS) in acute liver failure (ALF), in which infection is common, has not been… Expand
Review
1997
Review
1997
Systemic inflammatory response syndrome
Background Localized inflammation is a physiological protective response which is generally tightly controlled by the body at the… Expand
Review
1996
Review
1996
Immunologic Dissonance: A Continuing Evolution in Our Understanding of the Systemic Inflammatory Response Syndrome (SIRS) and the Multiple Organ Dysfunction Syndrome (MODS)
  • R. Bone
  • Annals of Internal Medicine
  • 1996
    • Corpus ID: 29851294
Fifty years ago, multiple organ failure was unheard ofwe could not keep patients alive long enough for the sequential dysfunction… Expand
Review
1996
Review
1996
Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation.
  • R. Bone
  • Critical care medicine
  • 1996
    • Corpus ID: 45806075
OBJECTIVES The systemic inflammatory response syndrome (SIRS) is the massive inflammatory reaction resulting from systemic… Expand
Review
1995
Review
1995
The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study.
OBJECTIVE Define the epidemiology of the four recently classified syndromes describing the biologic response to infection… Expand
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