Survival Motor Neuron Protein

Known as: Component of Gems 1, Gemin-1 
Survival motor neuron protein (294 aa, ~32 kDa) is encoded by the human SMN1 and SMN2 genes. This protein plays a role in the assembly of small… (More)

Topic mentions per year

Topic mentions per year

2008-2017
024620082017

Papers overview

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2018
2018
Spinal muscular atrophy (SMA) is an autosomal-recessive childhood motor neuron disease and the main genetic cause of infant… (More)
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2018
2018
The results from two clinical trials of novel therapies for spinal muscular atrophy (SMA) have been published in the New England… (More)
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2017
2017
BACKGROUND Spinal muscular atrophy (SMA) is the most common genetic neurological disease leading to infant death. It is caused by… (More)
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2017
2017
Spinal muscular atrophy (SMA) is caused by homozygous mutation of the survival motor neuron 1 (SMN1) gene. Disease severity… (More)
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2017
2017
Survival motor neuron (SMN) protein deficiency causes the genetic neuromuscular disorder spinal muscular atrophy (SMA… (More)
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2016
2016
BACKGROUND Spinal muscular atrophy is a neurodegenerative disorder caused by the deficient expression of survival motor neuron… (More)
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2015
2015
Spinal muscular atrophy (SMA) is a common autosomal recessive neuromuscular disorder that is currently incurable. SMA is caused… (More)
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2013
2013
Oxidative stress and survival motor neuron (Smn) protein deficiency are the major causes of motor neuronal death. Naloxone… (More)
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2012
2012
OBJECTIVES Survival Motor Neuron (SMN) protein levels may become key pharmacodynamic (PD) markers in spinal muscular atrophy (SMA… (More)
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2011
2011
Spinal muscular atrophy is a severe neurogenic disease that is caused by mutations in the human survival motor neuron 1 (SMN1… (More)
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