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Sublingual administration of active pharmaceutical substances is in principle favourable for rapid onset of drug action, ready… Expand The purpose of this study was to develop and optimize formulations of mucoadhesive bilayered buccal patches of sumatriptan… Expand The purpose of the present study was to develop intranasal delivery systems of sumatriptan using thermoreversible polymer… Expand CONTEXT
Multiple pathogenic mechanisms may be involved in generating the migraine symptom complex, and multimechanism-targeted… Expand The effects of percutaneous enhancers on the transdermal absorption of sumatriptan succinate were investigated by in vitro… Expand OBJECTIVE
To evaluate the impact of sumatriptan succinate injection compared with placebo on productivity loss during a migraine… Expand Sumatriptan succinate, a serotonin-1 (5-hydroxytryptamine-1) receptor agonist, is an antimigraine drug that is reported to act by… Expand BACKGROUND
Rizatriptan (MK-462) is a new 5-hydroxytryptamine1D (serotonin1D; 5-HT1D) receptor agonist for the acute treatment of… Expand OBJECTIVE
To assess the efficacy and tolerability of subcutaneous dihydroergotamine mesylate (DHE-45) vs subcutaneous sumatriptan… Expand Sumatriptan succinate, a 5-HT1D receptor agonist, constricts human cranial arteries. Two parallel-group trials for treatment of… Expand