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Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Sertindole Study Group.
OBJECTIVE This multicenter, double-blind, placebo-controlled study evaluated the efficacy and safety of three doses of sertindole (12, 20, and 24 mg/day) and haloperidol (4, 8, and 16 mg/day) in theExpand
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Evaluation of the pharmacokinetic profiles of the new testosterone topical gel formulation, Testim™, compared to AndroGel®
A two‐period, randomized, complete crossover study was performed to evaluate the pharmacokinetic profiles of Testim™ (AA2500), a new 1% testosterone topical gel formulation, compared to AndroGel®, anExpand
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A randomized, controlled, dose-ranging trial of sertindole in patients with schizophrenia
Sertindole is a novel antipsychotic agent with high selectivity for the mesolimbic dopaminergic pathway and nanomolar affinities for dopamine D2, serotonin 5-HT2, and norepinephrine NEα1 receptors.Expand
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Zelrix™: A Novel Transdermal Formulation of Sumatriptan
Objective.— This study evaluated the pharmacokinetic and tolerability profiles of Zelrix™ (NuPathe Inc., Conshohocken, PA, USA), the novel formulation of sumatriptan (formerly known as NP101).
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Identification of Psychoactive Degradants of Cannabidiol in Simulated Gastric and Physiological Fluid
Abstract Introduction: In recent research, orally administered cannabidiol (CBD) showed a relatively high incidence of somnolence in a pediatric population. Previous work has suggested that when CBDExpand
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AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function.
Testosterone replacement in hypogonadal men improves body composition, mood, and sexual functioning. In this 90-d study, we compared the pharmacokinetics and treatment effectiveness of a topicalExpand
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A Unique Iontophoretic Patch for Optimal Transdermal Delivery of Sumatriptan
PurposeMigraines affect approximately 10% of the adult population worldwide. The purpose of this study was to assess the pharmacokinetic and safety profile of a novel iontophoretic sumatriptanExpand
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A Sumatriptan Iontophoretic Transdermal System for the Acute Treatment of Migraine
Objective.— Gastrointestinal symptoms, such as nausea and vomiting, occur almost universally at one time or another in patients during a migraine attack. One third of patients who experienceExpand
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The Efficacy of Transdermal Sumatriptan Is Too Low for General Use – a Response
Headache carries the subtitle, the journal of head and face pain. A chance encounter years ago led to my attendance at a meeting of the American Association for the Study of Headache (AASH), now theExpand
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AA 2500 Testosterone Gel Normalizes Androgen Levels in Aging Males with Improvements in Body Composition and Sexual Function
Testosterone replacement in hypogonadal men improves body composition, mood, and sexual functioning. In this 90-d study, we compared the pharmacokinetics and treatment effectiveness of a topicalExpand
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