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Sulfalene

Known as: Sulfalenum, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine, Solfametopirazina 
A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health

Papers overview

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2011
2011
A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of… Expand
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2009
2009
Background This study was conducted to determine the efficacy of the antimalarial artemisinin-based combination therapy (ACT… Expand
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2008
2008
Abstract Although artemisinin and its derivatives are widely used for the treatment of malaria, they also have antischistosomal… Expand
Highly Cited
2007
Highly Cited
2007
BackgoundSulphadoxine/sulphalene-pyrimethamine (SP) was adopted in Kenya as first line therapeutic for uncomplicated malaria in… Expand
Highly Cited
2007
Highly Cited
2007
The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte… Expand
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2006
2006
The choice of artemisinin-based combination that is being adopted for malaria treatment in sub-Saharan Africa may depend on… Expand
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Review
1993
Review
1993
Trimethoprim is the best known inhibitor of bacterial dihydrofolate reductase. Initially, this was always combined with… Expand
1975
1970
1970
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens… Expand
1968
1968
The combination of a long-acting sulfonamide, sulfalene, and a dihydrofolic acid reductase inhibitor, trimethoprim, proved to be… Expand