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Sulfalene

Known as: Sulfalenum, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine, Solfametopirazina 
A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Anti-Infective AgentsAnti-Infective Agents, UrinaryAntimalarials
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

KelfizinaKelfizinekelfiprimmetakelfin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of… 
2009
2009
Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children
Background This study was conducted to determine the efficacy of the antimalarial artemisinin-based combination therapy (ACT… 
Review
2008
Review
2008
A Nationwide Survey of the Quality of Antimalarials in Retail Outlets in Tanzania
Introduction Retail pharmaceutical products are commonly used to treat fever and malaria in sub-Saharan African countries. Small… 
2008
2008
The antischistosomal efficacies of artesunate–sulfamethoxypyrazine–pyrimethamine and artemether–lumefantrine administered as treatment for uncomplicated, Plasmodium falciparum malaria
Abstract Although artemisinin and its derivatives are widely used for the treatment of malaria, they also have antischistosomal… 
Highly Cited
2007
Highly Cited
2007
The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya
BackgoundSulphadoxine/sulphalene-pyrimethamine (SP) was adopted in Kenya as first line therapeutic for uncomplicated malaria in… 
Highly Cited
2007
Highly Cited
2007
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern…
The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte… 
2006
2006
A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.
The choice of artemisinin-based combination that is being adopted for malaria treatment in sub-Saharan Africa may depend on… 
Review
1993
Review
1993
Reassessment of the rationale for the combinations of sulphonamides with diaminopyrimidines.
Trimethoprim is the best known inhibitor of bacterial dihydrofolate reductase. Initially, this was always combined with… 
1970
1970
Single-dose Therapy with Streptomycin and Sulfametopyrazine for Bacteriuria during Pregnancy
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens… 
1968
1968
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
The combination of a long-acting sulfonamide, sulfalene, and a dihydrofolic acid reductase inhibitor, trimethoprim, proved to be… 
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