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Sulfalene

Known as: Sulfalenum, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine, Solfametopirazina 
A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Anti-Infective AgentsAnti-Infective Agents, UrinaryAntimalarials
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (4)

KelfizinaKelfizinekelfiprimmetakelfin

Papers overview

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Highly Cited
2012
Highly Cited
2012
Why Use of Interventions Targeting Outdoor Biting Mosquitoes will be Necessary to Achieve Malaria Elimination
By definition, elimination of malaria means permanent reduction to zero of locally incidence of infections. Achieving this goal… Expand
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2010
2010
Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial.
BACKGROUND Schistosomiasis is an important parasitic disease in Kenya. Decreasing susceptibility of schistosomes to praziquantel… Expand
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2009
2009
Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children
BACKGROUND This study was conducted to determine the efficacy of the antimalarial artemisinin-based combination therapy (ACT… Expand
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2008
2008
The antischistosomal efficacies of artesunate–sulfamethoxypyrazine–pyrimethamine and artemether–lumefantrine administered as treatment for uncomplicated, Plasmodium falciparum malaria
Abstract Although artemisinin and its derivatives are widely used for the treatment of malaria, they also have antischistosomal… Expand
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Highly Cited
2007
Highly Cited
2007
The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya
BackgoundSulphadoxine/sulphalene-pyrimethamine (SP) was adopted in Kenya as first line therapeutic for uncomplicated malaria in… Expand
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2007
2007
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern…
The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte… Expand
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2007
2007
Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine: artesunate…
In view of the changing policy towards artemisinin-based combination therapies (ACTs), the efficacy, tolerance, and degree of re… Expand
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Review
1993
Review
1993
Reassessment of the rationale for the combinations of sulphonamides with diaminopyrimidines.
Trimethoprim is the best known inhibitor of bacterial dihydrofolate reductase. Initially, this was always combined with… Expand
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1975
1975
Laboratory and clinical studies with sulfametopyrazine as a treatment for bacteriuria in pregnancy.
  • D. S. Reeves
  • The Journal of antimicrobial chemotherapy
  • 1975
    • Corpus ID: 39284877
 
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1970
1970
Single-dose therapy with streptomycin and sulfametopyrazine for bacteriuria during pregnancy.
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens… Expand
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