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Sulfalene
Known as:
Sulfalenum
, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine
, Solfametopirazina
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A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health
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Related topics
Related topics
14 relations
Broader (3)
Anti-Infective Agents
Anti-Infective Agents, Urinary
Antimalarials
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Narrower (4)
Kelfizina
Kelfizine
kelfiprim
metakelfin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
N. Boechat
,
Luiz C. S. Pinheiro
,
O. Santos-Filho
,
I. C. Silva
Molecules
2011
Corpus ID: 15110616
A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of…
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2009
2009
Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children
M. Sissoko
,
A. Dabo
,
+13 authors
O. Doumbo
PloS one
2009
Corpus ID: 3819949
Background This study was conducted to determine the efficacy of the antimalarial artemisinin-based combination therapy (ACT…
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Review
2008
Review
2008
A Nationwide Survey of the Quality of Antimalarials in Retail Outlets in Tanzania
H. Kaur
,
C. Goodman
,
+4 authors
S. Abdulla
PloS one
2008
Corpus ID: 3272690
Introduction Retail pharmaceutical products are commonly used to treat fever and malaria in sub-Saharan African countries. Small…
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2008
2008
The antischistosomal efficacies of artesunate–sulfamethoxypyrazine–pyrimethamine and artemether–lumefantrine administered as treatment for uncomplicated, Plasmodium falciparum malaria
I. Adam
,
O. Elhardello
,
M. Elhadi
,
E. Abdalla
,
K. Elmardi
,
F. Jansen
Annals of tropical medicine and parasitology
2008
Corpus ID: 33522390
Abstract Although artemisinin and its derivatives are widely used for the treatment of malaria, they also have antischistosomal…
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Highly Cited
2007
Highly Cited
2007
The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya
A. Amin
,
D. Zurovac
,
+4 authors
R. Snow
Malaria Journal
2007
Corpus ID: 11657750
BackgoundSulphadoxine/sulphalene-pyrimethamine (SP) was adopted in Kenya as first line therapeutic for uncomplicated malaria in…
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Highly Cited
2007
Highly Cited
2007
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern…
A. Sowunmi
,
G. Gbotosho
,
+5 authors
B. Fateye
The American journal of tropical medicine and…
2007
Corpus ID: 23521978
The treatment efficacy and effects of artemether-lumefantrine (AL) and amodiaquine-sulfalene-pyrimethamine (ASP) on gametocyte…
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2006
2006
A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.
I. Sagara
,
A. Dicko
,
+10 authors
O. Doumbo
The American journal of tropical medicine and…
2006
Corpus ID: 42181093
The choice of artemisinin-based combination that is being adopted for malaria treatment in sub-Saharan Africa may depend on…
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Review
1993
Review
1993
Reassessment of the rationale for the combinations of sulphonamides with diaminopyrimidines.
W. Brumfitt
,
J. Hamilton-miller
Journal of chemotherapy
1993
Corpus ID: 21234599
Trimethoprim is the best known inhibitor of bacterial dihydrofolate reductase. Initially, this was always combined with…
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1970
1970
Single-dose Therapy with Streptomycin and Sulfametopyrazine for Bacteriuria during Pregnancy
J. Williams
,
E. Smith
British medical journal
1970
Corpus ID: 9507089
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens…
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1968
1968
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
D. Martin
,
J. Arnold
JAMA
1968
Corpus ID: 2054865
The combination of a long-acting sulfonamide, sulfalene, and a dihydrofolic acid reductase inhibitor, trimethoprim, proved to be…
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