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Sulfalene

Known as: Sulfalenum, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine, Solfametopirazina 
A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Anti-Infective AgentsAnti-Infective Agents, UrinaryAntimalarials
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

KelfizinaKelfizinekelfiprimmetakelfin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of… 
Highly Cited
2009
Highly Cited
2009
Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children
Background This study was conducted to determine the efficacy of the antimalarial artemisinin-based combination therapy (ACT… 
Review
2008
Review
2008
A Nationwide Survey of the Quality of Antimalarials in Retail Outlets in Tanzania
Introduction Retail pharmaceutical products are commonly used to treat fever and malaria in sub-Saharan African countries. Small… 
2006
2006
A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.
The choice of artemisinin-based combination that is being adopted for malaria treatment in sub-Saharan Africa may depend on… 
1994
1994
Sulphadoxine concentrations in plasma, red blood cells and whole blood in healthy and Plasmodium falciparum malaria cases after treatment with Fansidar using high-performance liquid chromatography.
1975
1975
Laboratory and clinical studies with sulfametopyrazine as a treatment for bacteriuria in pregnancy.
1973
1973
Polymorphic acetylation of drugs in rabbits.
Abstract1. Polymorphism for the acetylation of sulphamethazine was demonstrated in rabbits based on levels of the parent drug and… 
1971
1971
Plasmodium knowlesi: in vitro evaluation of antimalarial activity of folic acid inhibitors.
1970
1970
Single-dose Therapy with Streptomycin and Sulfametopyrazine for Bacteriuria during Pregnancy
One hundred and sixty-three patients with bacteriuria in pregnancy were treated with a single dose of antibiotic. Four regimens… 
1968
1968
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
  • D. MartinJ. Arnold
  • Journal of the American Medical Association (JAMA…
  • 1968
  • Corpus ID: 2054865
The combination of a long-acting sulfonamide, sulfalene, and a dihydrofolic acid reductase inhibitor, trimethoprim, proved to be… 
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