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Sulfalene

Known as: Sulfalenum, 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine, Solfametopirazina 
A long-acting sulfonamide antibiotic used for the treatment of chronic bronchitis, urinary tract infections and malaria.
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Anti-Infective AgentsAnti-Infective Agents, UrinaryAntimalarials
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (4)

KelfizinaKelfizinekelfiprimmetakelfin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Artesunate plus sulfamethoxypyrazine/pyrimethamine for the treatment of cutaneous leishmaniasis: a double-blind, placebo-controlled clinical trial.
2008
2008
Single-day, three-dose treatment with fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine to cure Plasmodium falciparum malaria.
1994
1994
Sulphadoxine concentrations in plasma, red blood cells and whole blood in healthy and Plasmodium falciparum malaria cases after treatment with Fansidar using high-performance liquid chromatography.
1980
1980
Pharmacokinetic study of a sulfametopyrazine/trimethoprim combination (Kelfiprim) in human volunteers.
1979
1979
Structural changes of Toxoplasma gondii bradyzoites and cysts following therapy with sulfamethoxypyrazine-pyrimethamine: studies by light and electron microscopy. Consequences for chemotherapy.
Mastomys natalensis chronically infected with Toxoplasma gondii strain ALT over two months were treated with sulfamethoxypyrazine… 
1976
1976
Haemolytic Effect of Two Sulphonamides Evaluated by a New Method
A technique to investigate drugs which could cause haemolysis in subjects deficient in glucosc‐6‐phosphate dehydrogenase (D… 
1975
1975
Host failure in treatment of malaria with sulfalene and pyrimethamine.
An individual infected with a multidrug-resistant strain of Plasmodium falciparum failed to respond to treatment with sulfalene… 
1973
1973
Polymorphic acetylation of drugs in rabbits.
Abstract1. Polymorphism for the acetylation of sulphamethazine was demonstrated in rabbits based on levels of the parent drug and… 
1971
1971
Plasmodium knowlesi: in vitro evaluation of antimalarial activity of folic acid inhibitors.
1968
1968
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
  • D. MartinJ. Arnold
  • Journal of the American Medical Association (JAMA…
  • 1968
  • Corpus ID: 2054865
The combination of a long-acting sulfonamide, sulfalene, and a dihydrofolic acid reductase inhibitor, trimethoprim, proved to be… 
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