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Substance-P Receptor, Human

Known as: NKIR, Substance-P Receptor, NK-1R 
Substance-P receptor (407 aa, ~46 kDa) is encoded by the human TACR1 gene. This protein is involved in tachykinin-dependent G protein-coupled… 
National Institutes of Health

Related topics

Related topics

12 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane ProteinsLigand Binding

Broader (1)

Substance P Receptor

Papers overview

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Highly Cited
2004
Highly Cited
2004
Recycling and Resensitization of the Neurokinin 1 Receptor
Substance P (SP) induces endocytosis and recycling of the neurokinin 1 receptor (NK1R) in endothelial cells and spinal neurons at… 
2003
2003
A neurokinin 1 receptor antagonist reduces an ongoing ileal pouch inflammation and the response to a subsequent inflammatory stimulus.
Ileal pouch-anal anastomosis (IPAA) is an excellent surgical option for patients with chronic ulcerative colitis (CUC) requiring… 
Highly Cited
2001
Highly Cited
2001
Dynamin and Rab5a-dependent Trafficking and Signaling of the Neurokinin 1 Receptor*
Understanding the molecular mechanisms of agonist-induced trafficking of G-protein-coupled receptors is important because of the… 
Highly Cited
2000
Highly Cited
2000
Spinal lamina I neurons that express neurokinin 1 receptors: morphological analysis
Highly Cited
1999
Highly Cited
1999
An Improved Shear Lag Model for Broken Fibers in Composite Materials
A shear lag model is formulated to predict the stresses in a unidirectional fiber reinforced composite. The model is based on… 
Highly Cited
1997
Highly Cited
1997
Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters
The major differentiation products of maturing keratinocytes contain AP-1 regulatory motifs, and AP-1 DNA binding activity… 
Highly Cited
1996
Highly Cited
1996
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons
Highly Cited
1993
Highly Cited
1993
Beam quality specification for photon beam dosimetry.
It is argued that %dd(10), the percentage depth dose at 10 cm in a 10 x 10 cm2 photon beam at a SSD of 100 cm, is a better beam… 
Highly Cited
1979
Highly Cited
1979
ATP-dependent renaturation of DNA catalyzed by the recA protein of Escherichia coli.
The product of the recA gene of Escherichia coli has been purified to near-homogeneity by a simple three-step procedure… 
Highly Cited
1957
Highly Cited
1957
Possible molecular models for gramicidin S and their relationship to present ideas of protein structure.
Campbell, W. R. & Hanna, M. I. (1937). J. biol. Chem. 11i, 1. Conant, J. B., Kirner, W. R. & Hussey, R. E. (1925). J. Amer. chem… 
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