Substance-P Receptor, Human

Known as: NKIR, Substance-P Receptor, NK-1R 
Substance-P receptor (407 aa, ~46 kDa) is encoded by the human TACR1 gene. This protein is involved in tachykinin-dependent G protein-coupled… (More)
National Institutes of Health

Related topics

Related topics

12 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane ProteinsLigand Binding
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Substance P Receptor

Papers overview

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Highly Cited
2012
Highly Cited
2012
Asynchronous Physical-Layer Network Coding
A key issue in physical-layer network coding (PNC) is how to deal with the asynchrony between signals transmitted by multiple… (More)
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Highly Cited
2008
Highly Cited
2008
Implementing workplace-based assessment across the medical specialties in the United Kingdom.
OBJECTIVES To evaluate the reliability and feasibility of assessing the performance of medical specialist registrars (SpRs) using… (More)
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Highly Cited
2006
Highly Cited
2006
Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord.
Blockade of local spinal cord inhibition mimics the behavioral hypersensitivity that manifests in chronic pain states. This… (More)
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Highly Cited
2004
Highly Cited
2004
Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant
BACKGROUND Aprepitant is a highly selective substance P (neurokinin 1 [NK(1)] receptor) antagonist that significantly improves… (More)
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Highly Cited
2002
Highly Cited
2002
Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation.
Lamina I of the spinal cord is densely innervated by nociceptive primary afferents, many of which contain substance P. It… (More)
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Highly Cited
1998
Highly Cited
1998
Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury.
Substance P, acting via the neurokinin 1 receptor (NK1R), plays an important role in mediating a variety of inflammatory… (More)
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Highly Cited
1997
Highly Cited
1997
English Relative Clause Constructions ∗
Abstract This paper sketches a grammar of English relative clause constructions (including infinitival and reduced relatives… (More)
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Highly Cited
1992
Highly Cited
1992
Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.
We have constructed cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. All vectors… (More)
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Highly Cited
1991
Highly Cited
1991
Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3.
The molecular basis of the mouse mutation splotch (Sp), which is associated with spina bifida and exencephaly, was analyzed at… (More)
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Highly Cited
1989
Highly Cited
1989
New derivatives of transposon Tn5 suitable for mobilization of replicons, generation of operon fusions and induction of genes in gram-negative bacteria.
Three types of new variants of the broad-host-range transposon Tn5 are described. (i) Tn5-mob derivatives with the new selective… (More)
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