Structure of lumen of body system

Known as: Lumen, lumens 
The cavity or channel within a tube or tubular organ such as a blood vessel or the intestine.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Molecular Regulation of Lumen Morphogenesis
The asymmetric polarization of cells allows specialized functions to be performed at discrete subcellular locales. Spatiotemporal… (More)
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Review
2007
Review
2007
Biogenesis and function of multivesicular bodies.
The two major cellular sites for membrane protein degradation are the proteasome and the lysosome. Ubiquitin attachment is a… (More)
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Highly Cited
2005
Highly Cited
2005
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish.
Tube and lumen formation are essential steps in forming a functional vasculature. Despite their significance, our understanding… (More)
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Highly Cited
2004
Highly Cited
2004
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
Elimination of misfolded proteins from the endoplasmic reticulum (ER) by retro-translocation is an important physiological… (More)
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Highly Cited
2000
Highly Cited
2000
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
ATF6 is a membrane-bound transcription factor that activates genes in the endoplasmic reticulum (ER) stress response. When… (More)
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Highly Cited
1998
Highly Cited
1998
Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology.
OBJECTIVES This study was designed to evaluate whether calcium deposition in the coronary arteries is related to atherosclerotic… (More)
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Highly Cited
1996
Highly Cited
1996
Patterns and mechanisms of in-stent restenosis. A serial intravascular ultrasound study.
BACKGROUND Studies have suggested that restenosis within Palmaz-Schatz stents results from neointimal hyperplasia or chronic… (More)
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Highly Cited
1992
Highly Cited
1992
Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model.
Restenosis is a reparative response to arterial injury occurring with percutaneous coronary revascularization. However, the… (More)
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Highly Cited
1992
Highly Cited
1992
Lumen diameter of normal human coronary arteries. Influence of age, sex, anatomic variation, and left ventricular hypertrophy or dilation.
BACKGROUND Precise knowledge of the expected "normal" lumen diameter at a given coronary anatomic location is a first step toward… (More)
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Highly Cited
1987
Highly Cited
1987
Compensatory enlargement of human atherosclerotic coronary arteries.
Whether human coronary arteries undergo compensatory enlargement in the presence of coronary disease has not been clarified. We… (More)
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